Bacterial isolates will be purchased from ATCC and their beta-lactam antibiotic susceptibility will be measured with the proposed assay and compared against other susceptibility results generated using conventional methodologies. We expect the IRB will determine that this does not meet thte definition of human subjects research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54EB015408-01
Application #
8467243
Study Section
Special Emphasis Panel (ZEB1-OSR-D (M2))
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
1
Fiscal Year
2012
Total Cost
$176,433
Indirect Cost
$75,180
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Liang, Li-Guo; Kong, Meng-Qi; Zhou, Sherry et al. (2017) An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer. Sci Rep 7:46224
Liang, Li-Guo; Sheng, Ye-Feng; Zhou, Sherry et al. (2017) An Integrated Double-Filtration Microfluidic Device for Detection of Extracellular Vesicles from Urine for Bladder Cancer Diagnosis. Methods Mol Biol 1660:355-364
Batsis, John A; Pletcher, Sarah N; Stahl, James E (2017) Telemedicine and primary care obesity management in rural areas - innovative approach for older adults? BMC Geriatr 17:6
Sher, Mazhar; Zhuang, Rachel; Demirci, Utkan et al. (2017) Paper-based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms. Expert Rev Mol Diagn 17:351-366
Sauer-Budge, Alexis F; Brookfield, Samuel J; Janzen, Ronald et al. (2017) A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One 12:e0183625
Asghar, Waseem; Yuksekkaya, Mehmet; Shafiee, Hadi et al. (2016) Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications. Sci Rep 6:21163
Wang, ShuQi; Chinnasamy, Thiruppathiraja; Lifson, Mark A et al. (2016) Flexible Substrate-Based Devices for Point-of-Care Diagnostics. Trends Biotechnol 34:909-921
Rodriguez, Natalia M; Wong, Winnie S; Liu, Lena et al. (2016) A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples. Lab Chip 16:753-63
Lifson, Mark A; Ozen, Mehmet Ozgun; Inci, Fatih et al. (2016) Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring. Adv Drug Deliv Rev 103:90-104
Wang, ShuQi; Lifson, Mark A; Inci, Fatih et al. (2016) Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev Mol Diagn 16:449-59

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