Overall The Point-of-Care Technology Research Center in Primary Care proposes to further develop a national ?center-without-walls? for rapid transformation of emerging point-of-care technologies into commercially viable, clinically focused solutions for improving primary healthcare. The Center was established by the Consortia for Improving Medicine through Innovation and Technology (CIMIT), a consortium of research institutions, universities, military medicine centers and hospitals throughout the US with international affiliates at University of Manchester-UK (MIMIT), Barcelona (The Center for the Integration of Medicine and Innovative Technologies in Catalonia) and Singapore (A*-STAR/Eastern Health Alliance). CIMIT established the Point-of- Care Technology Research Center in Primary Care under a Cooperative Agreement (U54) award from National Institute of Biomedical Imaging and Bioengineering (NIBIB) in 2012 and the Center created a national network of research sites, harnessing the power of multidisciplinary collaboration to speed the translation of high-impact research into primary care practice and broader dissemination by commercially licensable opportunities. We will build upon our proven approach to needs-driven primary healthcare technology innovation to expand and significantly enhance our Center. The Center?s overall objective is to build upon the progress made under the previous U54 award and offer expanded support to teams through the integrated functional elements of the proposed enhanced Center. In so doing, the Center will offer a portfolio of synergistic support to teams with innovative solutions through defined interfaces and hand offs throughout the innovation process while continuously improving the Center?s processes of finding, funding, facilitating, and following projects. The long-term goal is to create a dynamic, sustainable national network that identifies key unmet needs in the delivery of primary care as well as promising emerging technologies and then to accelerate their translation into clinical applications for broad impact in primary care medicine through high-quality translational and clinical research.

Public Health Relevance

Projects Narrative: Just as the mandate for primary care is growing with an aging population and an increase in people afflicted by chronic disease, the number of primary care providers is shrinking. This imbalance puts huge constraints on primary care capacity, limiting access and fragmenting care, jeopardizing health outcomes by delaying treatment, and complicating follow-up regarding treatment recommendations. The use of appropriately-designed point-of-care technologies in primary care environments will address these problems by increasing the capacity of primary care physicians to care for more patients and help them achieve better health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB015408-08
Application #
9916752
Study Section
Special Emphasis Panel (ZEB1)
Program Officer
Lash, Tiffani Bailey
Project Start
2012-07-01
Project End
2023-05-31
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
8
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02114
Liang, Li-Guo; Kong, Meng-Qi; Zhou, Sherry et al. (2017) An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer. Sci Rep 7:46224
Liang, Li-Guo; Sheng, Ye-Feng; Zhou, Sherry et al. (2017) An Integrated Double-Filtration Microfluidic Device for Detection of Extracellular Vesicles from Urine for Bladder Cancer Diagnosis. Methods Mol Biol 1660:355-364
Batsis, John A; Pletcher, Sarah N; Stahl, James E (2017) Telemedicine and primary care obesity management in rural areas - innovative approach for older adults? BMC Geriatr 17:6
Sher, Mazhar; Zhuang, Rachel; Demirci, Utkan et al. (2017) Paper-based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms. Expert Rev Mol Diagn 17:351-366
Sauer-Budge, Alexis F; Brookfield, Samuel J; Janzen, Ronald et al. (2017) A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One 12:e0183625
Wang, ShuQi; Lifson, Mark A; Inci, Fatih et al. (2016) Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev Mol Diagn 16:449-59
Wang, Chien-Chung; Hennek, Jonathan W; Ainla, Alar et al. (2016) A Paper-Based ""Pop-up"" Electrochemical Device for Analysis of Beta-Hydroxybutyrate. Anal Chem 88:6326-33
El Assal, Rami; Gurkan, Umut A; Chen, Pu et al. (2016) 3-D Microwell Array System for Culturing Virus Infected Tumor Cells. Sci Rep 6:39144
Hassan, Umer; Watkins, Nicholas N; Reddy Jr, Bobby et al. (2016) Microfluidic differential immunocapture biochip for specific leukocyte counting. Nat Protoc 11:714-26
Asghar, Waseem; Yuksekkaya, Mehmet; Shafiee, Hadi et al. (2016) Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications. Sci Rep 6:21163

Showing the most recent 10 out of 45 publications