Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM074899-03
Application #
7468051
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
3
Fiscal Year
2007
Total Cost
$149,550
Indirect Cost
Name
Hauptman-Woodward Medical Research Institute
Department
Type
DUNS #
074025479
City
Buffalo
State
NY
Country
United States
Zip Code
14203
Sridharan, Rajashri; Zuber, Jeffrey; Connelly, Sara M et al. (2014) Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors. Biochim Biophys Acta 1838:15-33
Grant, Thomas D; Snell, Edward H; Luft, Joseph R et al. (2012) Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase. Nucleic Acids Res 40:3723-31
Luft, Joseph R; Snell, Edward H; Detitta, George T (2011) Lessons from high-throughput protein crystallization screening: 10 years of practical experience. Expert Opin Drug Discov 6:465-80
Luft, Joseph R; Wolfley, Jennifer R; Snell, Edward H (2011) What's in a drop? Correlating observations and outcomes to guide macromolecular crystallization experiments. Cryst Growth Des 11:651-663
Luthra, Amit; Zhu, Guangyu; Desrosiers, Daniel C et al. (2011) The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices. J Biol Chem 286:41656-68
Grant, Thomas D; Luft, Joseph R; Wolfley, Jennifer R et al. (2011) Small angle X-ray scattering as a complementary tool for high-throughput structural studies. Biopolymers 95:517-30
Clark, Kathleen M; Fedoriw, Nadia; Robinson, Katrina et al. (2010) Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography. Protein Expr Purif 71:207-23
Larson, Steven B; Day, John S; Nguyen, Chieugiang et al. (2010) Structure of bovine pancreatic ribonuclease complexed with uridine 5'-monophosphate at 1.60 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun 66:113-20
Luft, Joseph R; Furlani, Nicholas M; Nemoyer, Rachel E et al. (2010) Crystal cookery - using high-throughput technologies and the grocery store as a teaching tool. J Appl Crystallogr 43:1189-1207
Cumbaa, Christian A; Jurisica, Igor (2010) Protein crystallization analysis on the World Community Grid. J Struct Funct Genomics 11:61-9

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