We have organized the Consortium Administrative Core based on the premise that productive collaborations do not necessarily require physically proximity. However, to nurture and maximize their collective output the proper leadership and administrative structure must be in place. We recognize a need to set in place an effective environment to foster the full engagement of each investigator and their staffs in the total science picture and to provide the scope of resources that not only facilitates, but also enhances individual research. Thus, the key motivation behind the organization of the present administrative structure is """"""""efficient integration"""""""". This integrafion will be key to our hwo major goals: promofing the highest quality science and fostering breakthroughs in the projects that bind us together, as well as maximizing the Consortium's impact by disseminafing advances in membrane protein structure and dynamics within and beyond its virtual walls.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM087519-04
Application #
8541033
Study Section
Special Emphasis Panel (ZGM1-CBB-3)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
4
Fiscal Year
2013
Total Cost
$2,492,240
Indirect Cost
$427,872
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Molinarolo, Steven; Lee, Sora; Leisle, Lilia et al. (2018) Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel. J Biol Chem 293:4981-4992
Paz, Aviv; Claxton, Derek P; Kumar, Jay Prakash et al. (2018) Conformational transitions of the sodium-dependent sugar transporter, vSGLT. Proc Natl Acad Sci U S A 115:E2742-E2751
Brugarolas, Pedro; Sánchez-Rodríguez, Jorge E; Tsai, Hsiu-Ming et al. (2018) Development of a PET radioligand for potassium channels to image CNS demyelination. Sci Rep 8:607
Mahinthichaichan, Paween; Morris, Dylan M; Wang, Yi et al. (2018) Selective Permeability of Carboxysome Shell Pores to Anionic Molecules. J Phys Chem B 122:9110-9118
Li, Jing; Ostmeyer, Jared; Cuello, Luis G et al. (2018) Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel. J Gen Physiol 150:1408-1420
Kerr, Daniel; Tietjen, Gregory T; Gong, Zhiliang et al. (2018) Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins. Biochim Biophys Acta Biomembr 1860:2126-2133
Litvinov, Aleksei; Feintuch, Akiva; Un, Sun et al. (2018) Triple resonance EPR spectroscopy determines the Mn2+ coordination to ATP. J Magn Reson 294:143-152
Carrasquel-Ursulaez, Willy; Alvarez, Osvaldo; Bezanilla, Francisco et al. (2018) Determination of the Stoichiometry between ?- and ?1 Subunits of the BK Channel Using LRET. Biophys J 114:2493-2497
Kintzer, Alexander F; Green, Evan M; Dominik, Pawel K et al. (2018) Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc Natl Acad Sci U S A 115:E9095-E9104
Quick, Matthias; Abramyan, Ara M; Wiriyasermkul, Pattama et al. (2018) The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites. Proc Natl Acad Sci U S A 115:E7924-E7931

Showing the most recent 10 out of 282 publications