In the US, COVID-19 has unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in our Black communities. There is an urgent need to establish effective testing strategies in these communities as the Fall/Winter virus surges unfold. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in our region and is uniquely positioned to lead a community-engaged testing research project to determine differences in COVID-19 testing rates between community-based (churches, community centers, and schools) and medical clinic-based testing sites, and determine approaches that will increase uptake of testing in underserved Black communities in the South. We plan to address these issues using a two-pronged approach. First, we will use a community based participatory research approach to determine differences in SARS-CoV-2 testing rates across distinct types of test sites within five urban underserved Black communities in the American South. We will use a multimedia campaign to promote and conduct RT-PCR testing on salivary samples obtained from 2,000 adults at 1) medical clinics, 2) schools, 3) community centers, and 4) churches (in random order) within five ZIP codes with known low socioeconomic status (SES) and a high representation of Black residents. The primary outcome will be the number of tests performed at each type of test site. We will collect information on age, sex, race, BMI, employment, social determinants of health using an aggregate SES score to identify important correlates of testing rates. Second, we will further leverage our strong and well-integrated partnership with the Baton Rouge Mayor's Healthy City Initiative together with our LA CaTS Community Advisory Boards (CABs) to conduct community-based focus groups to obtain qualitative data about the perceptions and attitudes related to testing access and potential barriers affecting such. We will use this information to determine community-driven approaches that are effective in reducing barriers and create strategies to increase SARS-CoV-2 testing uptake in urban underserved Black communities. Results of this project will greatly increase our understanding of the factors that have led to a disproportionate COVID-19 health burden in these underserved populations and lay the groundwork for developing strategies to reduce these disparities in all underserved Black communities. Resulting data will inform the equitable deployment of future virus/flu testing and a SARS-CoV-2 vaccine.

Public Health Relevance

To date, there has been relatively limited success in implementing COVID-19 testing in large segments of the population, particularly in low income underserved Black communities who concomitantly carry a disproportionate burden of health disparity. The proposed project will determine the best strategy to conduct culturally sensitive COVID-19 testing for urban underserved Black communities in the South. This project will significantly increase our understanding of how to successfully deploy resources that will maximize participation in COVID-19 testing in poor urban underserved Black communities and will lay the groundwork for developing policies to carry out future virus testing and vaccination programs.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54GM104940-05S3
Application #
10258534
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Gao, Hongwei
Project Start
2020-11-17
Project End
2022-06-30
Budget Start
2020-11-17
Budget End
2021-06-30
Support Year
5
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Lsu Pennington Biomedical Research Center
Department
Type
Organized Research Units
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808
Nicklas, Theresa; Islam, Noemi G; Saab, Rabab et al. (2018) Validity of a Digital Diet Estimation Method for Use with Preschool Children. J Acad Nutr Diet 118:252-260
Duberstein, Paul R; Chen, Michael; Chapman, Benjamin P et al. (2018) Fatalism and educational disparities in beliefs about the curability of advanced cancer. Patient Educ Couns 101:113-118
Coulter, Ann A; Rebello, Candida J; Greenway, Frank L (2018) Centrally Acting Agents for Obesity: Past, Present, and Future. Drugs 78:1113-1132
Xu, Wanli; Luo, Zhenwu; Alekseyenko, Alexander V et al. (2018) Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection. Sci Rep 8:12863
Zhai, Yi; Fang, Zhide (2018) Locally Optimal Designs for Some Dose-Response Models With Continuous Endpoints. Commun Stat Theory Methods 47:3803-3819
Pannuti, Antonio; Filipovic, Aleksandra; Hicks, Chindo et al. (2018) Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors. PLoS One 13:e0194790
Newton Jr, Robert L; Carter, Leah A; Johnson, William et al. (2018) A Church-Based Weight Loss Intervention in African American Adults using Text Messages (LEAN Study): Cluster Randomized Controlled Trial. J Med Internet Res 20:e256
Katner, Adrienne; Pieper, Kelsey; Brown, Komal et al. (2018) Effectiveness of Prevailing Flush Guidelines to Prevent Exposure to Lead in Tap Water. Int J Environ Res Public Health 15:
McDougal, David Harry; Darpolor, Moses Morakortoi; DuVall, Marina Andreyevna et al. (2018) Glial acetate metabolism is increased following a 72-h fast in metabolically healthy men and correlates with susceptibility to hypoglycemia. Acta Diabetol :
Wang, Jing; Liu, Enqing; Wang, Yue et al. (2018) Association of early pregnancy body mass index and children's birth weight with risk of being overweight in childhood. Am J Hum Biol 30:e23174

Showing the most recent 10 out of 528 publications