Overview and Specific Aims The overall objective of the Clinical and Translational Pilot Grant (CTPG) KCA is to build clinical and translational research capacity and extramural funding success among researchers in the Western IDeA states. Clinical and Translational Research addressing the unique regional health issues of the Western Region IDeA states has been carried out mainly in colleges of science, liberal arts, and allied health sciences, in departments of public health, nursing, social work, psychology, and related programs. However, these projects and programs are often underfunded, struggling with inadequate infrastructure support, constrained by limited availability of faculty release time, isolated from one another, and limited in scope. Support from a comprehensive pilot project program will substantially accelerate these existing efforts and bring them to a level competitive for independent extramural funding. The last decade has seen an unprecedented increase in NIH-funded research within the Western Region IDeA states, largely due to the support from COBRE and INBRE programs. Overall, these COBRE and INBRE programs have been very successful, but they have been focused almost entirely on pre-clinical research. There has been little support or infrastructure available to help this talented cadre of pre-clinical investigators move into translational research. This KCA will implement a program to fund pilot grants supporting projects likely to lead to independent NIH funding for both clinical, and translational, investigators. Awards will be based on reviews of scientific merit and the alignment of the proposed research with the mission of the CTN-IN. We will solicit proposals for clinical and translational research projects on topics including, but not limited to, health issues and health care access among rural and vulnerable populations in the Western Region IDeA states. The funds devoted to this program will translate to a high yield return on investment as investigators develop interdisciplinary collaborations and generate proof of principal data to accelerate successful extramural grant funding, ultimately hastening the adoption of transformative health-related discoveries by health care providers.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Nevada Las Vegas
Las Vegas
United States
Zip Code
Gorsic, Maja; Tran, Minh Ha; Novak, Domen (2018) Cooperative Cooking: A Novel Virtual Environment for Upper Limb Rehabilitation. Conf Proc IEEE Eng Med Biol Soc 2018:3602-3605
Walch, Amanda; Loring, Philip; Johnson, Rhonda et al. (2018) A scoping review of traditional food security in Alaska. Int J Circumpolar Health 77:1419678
D?Antoni, Michelle L; Paul, Robert H; Mitchell, Brooks I et al. (2018) Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism. J Acquir Immune Defic Syndr 79:108-116
Thyagaraj, Suraj; Pahlavian, Soroush Heidari; Sass, Lucas R et al. (2018) An MRI-Compatible Hydrodynamic Simulator of Cerebrospinal Fluid Motion in the Cervical Spine. IEEE Trans Biomed Eng 65:1516-1523
Shan, Guogen; Bernick, Charles; Banks, Sarah (2018) Sample size determination for a matched-pairs study with incomplete data using exact approach. Br J Math Stat Psychol 71:60-74
Pfau, Jean C; Barbour, Christopher; Black, Brad et al. (2018) Analysis of autoantibody profiles in two asbestiform fiber exposure cohorts. J Toxicol Environ Health A 81:1015-1027
Darzi, Ali; Gaweesh, Sherif M; Ahmed, Mohamed M et al. (2018) Identifying the Causes of Drivers' Hazardous States Using Driver Characteristics, Vehicle Kinematics, and Physiological Measurements. Front Neurosci 12:568
Lim, Eunjung; Gandhi, Krupa; Davis, James et al. (2018) Prevalence of Chronic Conditions and Multimorbidities in a Geographically Defined Geriatric Population With Diverse Races and Ethnicities. J Aging Health 30:421-444
Shan, Guogen (2018) Exact confidence limits for the response rate in two-stage designs with over- or under-enrollment in the second stage. Stat Methods Med Res 27:1045-1055
D'Antoni, Michelle L; Mitchell, Brooks I; McCurdy, Sara et al. (2018) Cenicriviroc inhibits trans-endothelial passage of monocytes and is associated with impaired E-selectin expression. J Leukoc Biol 104:1241-1252

Showing the most recent 10 out of 109 publications