. The proposed Mississippi Center for Clinical and Translational Research (CCTR) is a large, complex enterprise that will take a multi-faceted approach to promote the scale and success of obesity- focused research at the three CCTR partner institutions?the University of Mississippi Medical Center, Tougaloo College, and the University of Southern Mississippi. The Tracking and Evaluation Core will produce and analyze in-depth information on the progress of CCTR components and programs toward short- and long- term goals; their success in completing performance milestones; demand, function, utilization, and effectiveness of CCTR initiatives; decision making processes and effectiveness of resource sharing, allocation of resources, and leveraging of additional resources; outreach and dissemination of CCTR resources, services, and accomplishments; capacity building, strategic partnership growth, and sustainability; and anticipated impediments. The Core will assess whether CCTR activities are implemented as planned and measure their impact, and will identify and monitor the strengths and weaknesses of each program and service. As appropriate, the Core will make recommendations to modify CCTR initiatives to better meet investigator needs, increase efficiency and quality of CCTR activities, and lower cost. These data, analyses, and recommendations will be shared with the CCTR Director, Steering Committee, and advisory committees to inform their decisions and allow them to realign CCTR assets and efforts as needed to increase the utilization and quality and lower costs of CCTR services and resources. This information will also be shared by Dr. Wilson, through the CCTR Annual Report, with NIGMS. The efforts of the Tracking and Evaluation Core will result in accountable, informed leadership and guide the allocation of available assets to maximize the CCTR's success in increasing the number and diversity of obesity researchers in Mississippi, increasing multi- institutional collaboration and overall research funding, and producing research that will reduce obesity and health disparities and improve health outcomes across Mississippi.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54GM115428-01
Application #
8947715
Study Section
Special Emphasis Panel (ZGM1-TWD-C (CT))
Project Start
Project End
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
1
Fiscal Year
2016
Total Cost
$303,701
Indirect Cost
$104,553
Name
University of Mississippi Medical Center
Department
Type
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Hong, Jaeyoung; Hatchell, Kathryn E; Bradfield, Jonathan P et al. (2018) Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations. J Clin Endocrinol Metab 103:1380-1392
Benson, Tyler W; Weintraub, Daniel S; Crowe, Matthew et al. (2018) Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding. Mol Cell Endocrinol 473:79-88
Emdin, Connor A; Khera, Amit V; Klarin, Derek et al. (2018) Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling. Circulation 137:222-232
Raffield, Laura M; Ellis, Jaclyn; Olson, Nels C et al. (2018) Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study. J Hum Genet 63:327-337
Floyd, J S; Sitlani, C M; Avery, C L et al. (2018) Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. Pharmacogenomics J 18:127-135
Seyerle, A A; Sitlani, C M; Noordam, R et al. (2018) Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics J 18:215-226
Mouton, Alan J; DeLeon-Pennell, Kristine Y; Rivera Gonzalez, Osvaldo J et al. (2018) Mapping macrophage polarization over the myocardial infarction time continuum. Basic Res Cardiol 113:26
Sung, Yun J (see original citation for additional authors) (2018) A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet 102:375-400
Jun, Goo; Manning, Alisa; Almeida, Marcio et al. (2018) Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A 115:379-384
Adeosun, Samuel O; Moore, Kyle H; Lang, David M et al. (2018) A Novel Fluorescence-Based Assay for the Measurement of Biliverdin Reductase Activity. React Oxyg Species (Apex) 5:35-45

Showing the most recent 10 out of 102 publications