The mission of the Administrative Core is to provide centralized and coordinated scientific, administrative, and financial management for the three Projects and the Human Ovary Tissue Bank within the Center. Our goals are: 1. To ensure information exchange and appropriate decision-making processes between the Center (represented by the Directors) and the Internal Advisory Board, External Advisory Board, the Research Coordinator, and the Steering Committee of the Specialized Cooperative Centers in Reproductive Research Program. 2. To facilitate research collaborations and interactions within the U54 Specialized Cooperative Centers in Reproductive Research Program. 3. To utilize the Internal and External Advisory Boards to the fullest advantage of the Center. 4. To integrate and facilitate the scientific interactions of the Research Projects and the Ovary Tissue Bank and their scientific staff within the Center. 5. To facilitate translation of basic research information to clinical application. 6. To marshal institutional and community resources in support of reproductive research. 7. To elevate the profile of reproductive research in the scientific and clinical communities via the Enrichment Program. 8. To ensure appropriate access and efficient usage of the Human Ovary Tissue Bank. The Human Ovary Tissue Bank will be administratively housed within the Administrative Core. The purpose of the Human Ovary Tissue Bank continues to be to facilitate the translation of basic science to clinical medicine in fertility and infertility in women by providing RNAase free sections of normal and abnormal human ovaries to NIH-funded investigators for in situ hybridization and immunohistochemistry ex periments.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HD012303-26
Application #
7312312
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
26
Fiscal Year
2006
Total Cost
$100,399
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
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Fernandez, Marina O; Sharma, Shweta; Kim, Sun et al. (2017) Obese Neuronal PPAR? Knockout Mice Are Leptin Sensitive but Show Impaired Glucose Tolerance and Fertility. Endocrinology 158:121-133
Yamada-Nomoto, Kaori; Yoshino, Osamu; Akiyama, Ikumi et al. (2017) PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-? and TNF-? in mononuclear cells by insulin-sensitizing drugs. Am J Reprod Immunol 78:
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Hou, Jingwen; Cook-Andersen, Heidi; Su, H Irene et al. (2016) 17-Hydroxyprogesterone responses to human chorionic gonadotropin are not associated with serum anti-Mullerian hormone levels among adolescent girls with polycystic ovary syndrome. J Pediatr Endocrinol Metab 29:835-40
Hoffmann, Hanne M; Trang, Crystal; Gong, Ping et al. (2016) Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. J Neurosci 36:3506-18
Kelley, Scott T; Skarra, Danalea V; Rivera, Alissa J et al. (2016) The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome. PLoS One 11:e0146509

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