Abstract

The Administrative Core of the Boston Children's Hospital / Harvard Medical School IDDRC enhances research and promotes the development of new therapies by supporting outstanding research focused on problems relevant to intellectual and developmental disabilities. The Core supports the financial and administrative management of core facilities, provides core services to aid in the training of young investigators and their trainees, and fosters overall ?centerness? to enhance and encourage collaboration between IDDRC investigators. Through active engagement with other IDDRC cores and investigators throughout the national IDDRC network, the core services provided by our IDDRC promote collaboration outside the institution to speed the development of effective clinical interventions in intellectual and developmental disabilities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HD090255-05
Application #
10003041
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
5
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
Boston Children's Hospital
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Nowak-Sliwinska, Patrycja; Alitalo, Kari; Allen, Elizabeth et al. (2018) Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis 21:425-532
Di Gioia, Silvio Alessandro; Shaaban, Sherin; Tüysüz, Beyhan et al. (2018) Recessive MYF5 Mutations Cause External Ophthalmoplegia, Rib, and Vertebral Anomalies. Am J Hum Genet 103:115-124
Shaaban, Sherin; MacKinnon, Sarah; Andrews, Caroline et al. (2018) Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Invest Ophthalmol Vis Sci 59:4054-4064
Tyssowski, Kelsey M; DeStefino, Nicholas R; Cho, Jin-Hyung et al. (2018) Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron 98:530-546.e11
Bardai, Farah H; Wang, Liqun; Mutreja, Yamini et al. (2018) A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo. J Neurosci 38:108-119
Modi, Meera E; Sahin, Mustafa (2018) The Way Forward for Mechanism-Based Therapeutics in Genetically Defined Neurodevelopmental Disorders. Clin Pharmacol Ther 104:603-606
Wong, Man Yan; Liu, Changliang; Wang, Shan Shan H et al. (2018) Liprin-?3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses. Proc Natl Acad Sci U S A 115:2234-2239
Wojcik, Monica H; Wierenga, Klaas J; Rodan, Lance H et al. (2018) Beta-Ketothiolase Deficiency Presenting with Metabolic Stroke After a Normal Newborn Screen in Two Individuals. JIMD Rep 39:45-54
Hong, Y Kate; Burr, Eliza F; Sanes, Joshua R et al. (2018) Heterogeneity of retinogeniculate axon arbors. Eur J Neurosci :
Sundberg, Maria; Tochitsky, Ivan; Buchholz, David E et al. (2018) Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin. Mol Psychiatry 23:2167-2183

Showing the most recent 10 out of 498 publications