Abstract

Provide oversight, logistics, outreach to promote interactions internally and externally, tracking of milestones and financial status of projects. Reach out to community investigators to promote the MLPCN and assist with assay development to maintain an assay pipeline.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HG005034-03
Application #
8139219
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
3
Fiscal Year
2010
Total Cost
$724,260
Indirect Cost

  Institution

Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205

  Publications

Rasmussen, Lynn; White, E Lucile; Bostwick, James R (2016) Acoustic Droplet Ejection Applications for High-Throughput Screening of Infectious Agents. J Lab Autom 21:188-97
Rasmussen, Lynn; Tigabu, Bersabeh; White, E Lucile et al. (2015) Adapting high-throughput screening methods and assays for biocontainment laboratories. Assay Drug Dev Technol 13:44-54
Schreiber, Stuart L; Kotz, Joanne D; Li, Min et al. (2015) Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell 161:1252-65
Matharu, Daljit S; Flaherty, Daniel P; Simpson, Denise S et al. (2014) Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity. J Med Chem 57:10314-28
Schroeder, Chad E; Yao, Tuanli; Sotsky, Julie et al. (2014) Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus. J Med Chem 57:8608-21
Atkins, Colm; Evans, Carrie W; Nordin, Brian et al. (2014) Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza. J Biomol Screen 19:936-46
Wang, Hongxia; Silva, Anisia J; Rasmussen, Lynn et al. (2013) A highly specific cell-based high-throughput screening assay for ligands of cyclic adenosine monophosphate receptor protein in gram-negative bacteria. Assay Drug Dev Technol 11:382-7
Wang, Hongxia; Zhang, Li; Silva, Anisia J et al. (2013) A quinazoline-2,4-diamino analog suppresses Vibrio cholerae flagellar motility by interacting with motor protein PomB and induces envelope stress. Antimicrob Agents Chemother 57:3950-9
Chung, Dong-Hoon; Moore, Blake P; Matharu, Daljit S et al. (2013) A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus. Virol J 10:19
Atkins, Colm; Evans, Carrie W; White, E Lucile et al. (2012) Screening methods for influenza antiviral drug discovery. Expert Opin Drug Discov 7:429-38

Showing the most recent 10 out of 17 publications