The Center for Big Data in Translational Genomics administrative support will facilitate the effective collaboration of team members across three countries in reaching Center research aims. This support will provide technical and administrative infrastructure to assess the effectiveness of the Center, technical infrastructure for compute platforms and software development spanning industry and academia, and it will support consortium-wide activities such as general collaboration, metadata analysis and sharing, and open competitions.

Public Health Relevance

By setting up infrastructure to operate openly and internationally, and with the participation of key players in industry, the Center will enable the global data and methods sharing necessary to bring genomics into the big data era, and thus obtain the statistical power we need to use genomics to understand disease and develop new precision treatments.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54HG007990-01
Application #
8932072
Study Section
Special Emphasis Panel (ZRG1-BST-R (52))
Program Officer
Brooks, Lisa
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
$309,039
Indirect Cost
$115,662
Name
University of California Santa Cruz
Department
Type
DUNS #
125084723
City
Santa Cruz
State
CA
Country
United States
Zip Code
95064
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Jain, Miten; Koren, Sergey; Miga, Karen H et al. (2018) Nanopore sequencing and assembly of a human genome with ultra-long reads. Nat Biotechnol 36:338-345
Computational Pan-Genomics Consortium (2018) Computational pan-genomics: status, promises and challenges. Brief Bioinform 19:118-135
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Jain, Miten; Olsen, Hugh E; Turner, Daniel J et al. (2018) Linear assembly of a human centromere on the Y chromosome. Nat Biotechnol 36:321-323
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Ellrott, Kyle; Bailey, Matthew H; Saksena, Gordon et al. (2018) Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Syst 6:271-281.e7
Fiddes, Ian T; Armstrong, Joel; Diekhans, Mark et al. (2018) Comparative Annotation Toolkit (CAT)-simultaneous clade and personal genome annotation. Genome Res 28:1029-1038

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