The overall goal of the Administrative Core is to provide administrative support for the Comprehensive Center and to assist in the coordination of all Center activities. The Director of the St. Jude Comprehensive Sickle Cell Center, Dr. Russell Ware, will be responsible for the overall administrative oversight of the Center. He will be assisted by Dr. Arthur Nienhuis as the Scientific Co-Director and Dr. Winfred Wang as the Clinical Co-Director. Dr. Nienhuis will assist Dr. Ware in organizing the scientific activities of the Comprehensive Sickle Cell Center, and in particular with integration of the gene therapy initiatives into the Center, evaluation of its progress, and development of future plans for the Center. Dr. Wang will assist Dr. Ware in organizing and administration of the clinical aspects of the Center, and with the development and implementation of inter-Center projects proposed by the Comprehensive Center Steering Committee (SC). Drs. Ware, Nienhuis and Wang together have more than 80 years of combined experience in the participation and oversight of large clinical projects and research grants involving sickle cell disease. The Administrative Co-Director, Yvonne Carroll, RN JD, will be responsible for most of the day to day operations of the Center and will assist the Director and other Co-Directors with administrative responsibilities, including overseeing management and fiscal responsibilities.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HL070590-08
Application #
8261356
Study Section
Special Emphasis Panel (ZHL1)
Project Start
Project End
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
8
Fiscal Year
2011
Total Cost
$69,839
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Helton, Kathleen J; Glass, John O; Reddick, Wilburn E et al. (2015) Comparing segmented ASL perfusion of vascular territories using manual versus semiautomated techniques in children with sickle cell anemia. J Magn Reson Imaging 41:439-46
Carter, Robert; Wolf, Joshua; van Opijnen, Tim et al. (2014) Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions. Cell Host Microbe 15:587-599
Winchell, A M; Taylor, B A; Song, R et al. (2014) Evaluation of SWI in children with sickle cell disease. AJNR Am J Neuroradiol 35:1016-21
Nasimuzzaman, Md; Kim, Yoon-Sang; Wang, Yong-Dong et al. (2014) High-titer foamy virus vector transduction and integration sites of human CD34(+) cell-derived SCID-repopulating cells. Mol Ther Methods Clin Dev 1:14020
Henriques-Normark, Birgitta; Tuomanen, Elaine I (2013) The pneumococcus: epidemiology, microbiology, and pathogenesis. Cold Spring Harb Perspect Med 3:
Lebensburger, Jeffrey D; Howard, Thad; Hu, Yunming et al. (2012) Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin. Blood 119:1915-21
Mann, Beth; van Opijnen, Tim; Wang, Jianmin et al. (2012) Control of virulence by small RNAs in Streptococcus pneumoniae. PLoS Pathog 8:e1002788
McGann, Patrick T; Flanagan, Jonathan M; Howard, Thad A et al. (2012) Genotoxicity associated with hydroxyurea exposure in infants with sickle cell anemia: results from the BABY-HUG Phase III Clinical Trial. Pediatr Blood Cancer 59:254-7
Song, Ruitian; Loeffler, Ralf B; Hillenbrand, Claudia M (2012) QUIPSS II with window-sliding saturation sequence (Q2WISE). Magn Reson Med 67:1127-32
Nasimuzzaman, Md; Persons, Derek A (2012) Cell Membrane-associated heparan sulfate is a receptor for prototype foamy virus in human, monkey, and rodent cells. Mol Ther 20:1158-66

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