The Puerto Rico Clinical and Translational Research Consortium (PRCTRC) is an innovative model of collaboration, bringing together and leveraging the intellectual and physical resources of three major medical and health science centers in Puerto Rico: The University of Puerto Rico Medical Sciences Campus (UPRMSC), the Universidad del Caribe Central (UCC), and the Ponce School of Medicine &Health Sciences (PSM&HS) to address and reduce health disparities that most impact Hispanic populations. The mission is to serve as a vital and catalytic element in the efforts to understand, define, and address health disparities in Hispanic populations. Our efforts are guided by four strategic goals: 1) Facilitate the generation and translation of knowledge from the bench into the community by establishing a centralized program focused on reducing health disparities among Hispanic populations;2) Enhance and support existing training and mentoring programs to increase the number of new minority investigators in Clinical and Translational Research;3) Encourage collaborations among basic, clinical, and social scientists and community networks and health programs;and 4) Enhance and integrate existing infrastructure for clinical and translational research across Puerto Rico to support and expand Clinical and Translational Research in health disparities The PRCTRC has fostered a synergistic environment that supports research across the clinical and translational research continuum, with an emphasis on four disease states that post the greatest threats to Hispanic health: HIV/AIDS, neurological diseases, cardiovascular and metabolic diseases, and cancer. The PRCTRC provides this integrated infrastructure to investigators through nine Cores: Regulatory Knowledge and Support, Research Design and Biostatistics, clinical Research Resources and Facilities, Technology Resources for Core Laboratories, Biomedical Informatics, Collaborations and Partnerships, Professional Development, Clinical and Translational Pilot Project Program, and Community-based Research. Oversight is provided by an Administrative Core and formative and summative evaluation is provided by an Evaluation Core.

Public Health Relevance

Health disparities among underrepresented minorities constitute an important public health problem. This project proposes to generate important knowledge about the underlying causes and the most effective methods to reduce these health disparities among Hispanics. This project will also increase the participation of underrepresented minority investigators working on this problem.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54MD007587-04
Application #
8754896
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Zhang, Xinzhi
Project Start
2010-09-17
Project End
2019-04-30
Budget Start
2014-07-15
Budget End
2015-04-30
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936
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Rodriguez-Velazquez, Ariel; Velez, Rosa; Lafontaine, Jean Carlo et al. (2018) Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico. BMC Cancer 18:1177
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Ortiz, Ana Patricia; González, Daisy; Vivaldi-Oliver, José et al. (2018) Periodontitis and oral human papillomavirus infection among Hispanic adults. Papillomavirus Res 5:128-133
Pérez-Caraballo, Aixa M; Suarez, Erick; Unger, Elizabeth R et al. (2018) Seroprevalence of Human Papillomavirus (HPV) Type 6, 11, 16, 18, by Anatomic Site of HPV Infection, in Women Aged 16-64 Years living in the Metropolitan Area of San Juan, Puerto Rico. P R Health Sci J 37:26-31
Grover, Surbhi; Desir, Fidel; Jing, Yuezhou et al. (2018) Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. J Acquir Immune Defic Syndr 79:421-429
Diaz, Clemente; Lin, Leyi; Martinez, Luis J et al. (2018) Phase I Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults from Puerto Rico. Am J Trop Med Hyg 98:1435-1443
Preston, Alan M; Rodríguez-Orengo, José; González-Sepúlveda, Lorena et al. (2018) Effect of Housing Type on 25 OH Vitamin D in Serum of Rhesus Monkeys. P R Health Sci J 37:124-127

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