The Mid-South Transdisciplinary Collaborative Center for Health Disparities Research (Mid-South TCC), proposed by the University of Alabama at Birmingham, seeks to reduce the disparities in chronic disease burden experienced by African Americans in three Mid-South states (Alabama, Louisiana, and Mississippi), expand to another three Mid-South states (Arkansas, Tennessee, and Kentucky) and then nationally. The targeted Mid-South geographic area includes the most impoverished rural counties and inner-city communities in the nation, carrying exceptionally high burden of obesity, chronic diseases, and high mortality rates from these conditions. Our goal is to address the social determinants that interplay to impact a person's health and produce disparate health outcomes of minority populations. Specifically, we will focus on pathways to obesity and chronic illness and the mechanisms connecting these pathways to health disparities throughout the life-course. Our ultimate goal as a Mid-South TCC is to investigate all social, economic, cultural, and environmental factors driving and sustaining health disparities in obesity and chronic illnesses across the lifespan, and develop and implement interventions to ameliorate such disparities. This goal will be achieved through the following specific aims:
Aim 1. Conduct a one-year planning phase to: Solidify and expand the existing multi-sector Mid-South coalition in order to establish a regional infrastructure that will support the proposed research, implementation, and dissemination activities; Conduct a comprehensive assessment to identify existing relevant research, outreach capacities, policies and socioeconomic contexts, as well as barriers and needs unique to the targeted areas and population; Engage additional academic, community, and organizational/institutional partners and agencies to fill identified gaps; Identify areas of research to be developed and finalize procedures for pilot research projects; Develop a detailed plan and timelines for the program implementation.
Aim 2. Develop and implement a collaborative research program of regional research sub-projects; Establish 3 shared cores to support all Mid-South TCC research: Social Determinants of Health Measurement Core, Biostatistics/Study Design Core, and Academic-Community Engagement Core.
Aim 4. Implement a pilot project program, including a career development component;
Aim 5. Evaluate the research, implementation, and dissemination activities of the TCC.

Public Health Relevance

The Mid-South Transdisciplinary Collaborative Center for Health Disparities Research (Mid-South TCC) seeks to reduce the disparities in chronic disease burden experienced by African Americans in six Mid-South states. Our goal is to address the social determinants that interplay to impact a person's health and produce disparate health outcomes of minority populations. We will focus on pathways to obesity and chronic illness and the mechanisms connecting these pathways to health disparities throughout the life-course.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
4U54MD008176-05
Application #
9117309
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Berzon, Richard
Project Start
2012-09-26
Project End
2017-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
5
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Mwasongwe, Stanford E; Young, Bessie; Bidulescu, Aurelian et al. (2018) Relation of multi-marker panel to incident chronic kidney disease and rapid kidney function decline in African Americans: the Jackson Heart Study. BMC Nephrol 19:239
Clay, Olivio J; Perkins, Martinique; Wallace, Gail et al. (2018) Associations of Multimorbid Medical Conditions and Health-Related Quality of Life Among Older African American Men. J Gerontol B Psychol Sci Soc Sci 73:258-266
Cardel, Michelle I; Min, Yuan-I; Sims, Mario et al. (2018) Association of psychosocial stressors with metabolic syndrome severity among African Americans in the Jackson Heart Study. Psychoneuroendocrinology 90:141-147
Leggett, Sophia S; Wesley, Joan M; Myla, Anitha et al. (2018) Availability and Quality of Physical Activity Resources in Neighborhood Parks for Pregnant Women and Women of Childbearing Age. Prev Chronic Dis 15:E78
Danos, Denise; Leonardi, Claudia; Gilliland, Aubrey et al. (2018) Increased Risk of Hepatocellular Carcinoma Associated With Neighborhood Concentrated Disadvantage. Front Oncol 8:375
Danos, Denise M; Ferguson, Tekeda F; Simonsen, Neal R et al. (2018) Neighborhood disadvantage and racial disparities in colorectal cancer incidence: a population-based study in Louisiana. Ann Epidemiol 28:316-321.e2
Serrano-Gómez, Silvia J; Fejerman, Laura; Zabaleta, Jovanny (2018) Breast Cancer in Latinas: A Focus on Intrinsic Subtypes Distribution. Cancer Epidemiol Biomarkers Prev 27:3-10
Mwasongwe, Stanford; Min, Yuan-I; Booth 3rd, John N et al. (2018) Masked hypertension and kidney function decline: the Jackson Heart Study. J Hypertens 36:1524-1532
Bruce, Marino A; Martins, David; Duru, Kenrik et al. (2017) Church attendance, allostatic load and mortality in middle aged adults. PLoS One 12:e0177618
Stepanikova, Irena; Oates, Gabriela R; Bateman, Lori Brand (2017) Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender. Ethn Health 22:169-183

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