This proposal is in response to the Notice of Limited Competition for Specialized Neuroscience Research Programs (SNRPs) issued by NINDS. The main goal of our application is to build-upon the foundation set by the initial SNRP grant and strengthen the newly formed cluster in Cellular and Molecular Neuroscience at the University of Puerto Rico. This will be done by (i) funding three promising neuroscientists and directing them to become independent investigators with competitive research projects, (ii) fostering the neuroscience environment at UPR with an active seminar series where eminent neuroscientists are invited to present their work and to interact with local neuroscientists as well as by organizing meetings among local neuroscientists and (iii) setting up a training program in Neurosciences. The participating investigators include Annabell Segarra, from the Physiology Department of the Medical School collaborating with Craig Ferris of U.Mass., Eduardo Rosa-Molinar, of the Biology Dept. collaborating with Scott Fraser of Caltech and Joshua Rosenthal of the Institute of Neurobiology collaborating with Miguel Holmgren and Kenton Swartz of NIH. The SNRP Director will be Dr. Jose E. Garcia-Arraras, Professor in the Biology Department who has extensive experience in directing research programs. The Program will have a huge impact on Neuroscience in Puerto Rico by uniting in a cohesive working group some of the most active researchers, graduate and undergraduate student from the Institute of Neurobiology, the Biology Dept and the Physiology Dept. of the University of Puerto Rico. The Program will also enhance the research infrastructure providing equipment and technique transfers to various laboratories. Finally, SNRP will provide the structure needed to continue scientific studies initiated in the previous SNRP and to establish the first Training Program in Neurosciences in Puerto Rico.
| Mosquera, Laurivette; Shepherd, Luz; Torrado, Aranza I et al. (2015) Comparison of Two Methods of Estradiol Replacement: their Physiological and Behavioral Outcomes. J Vet Sci Technol 6:276 |
| Rosas, Odrick R; Torrado, Aranza I; Santiago, Jose M et al. (2014) Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res 9:2164-73 |
| Serrano-Velez, Jose L; Rodriguez-Alvarado, Melanie; Torres-Vazquez, Irma I et al. (2014) Abundance of gap junctions at glutamatergic mixed synapses in adult Mosquitofish spinal cord neurons. Front Neural Circuits 8:66 |
| Segarra, Annabell C; Torres-Díaz, Yvonne M; Silva, Richard D et al. (2014) Estrogen receptors mediate estradiol's effect on sensitization and CPP to cocaine in female rats: role of contextual cues. Horm Behav 65:77-87 |
| Santiago, José M; Torrado, Aranza I; Arocho, Luz C et al. (2013) Expression profile of flotillin-2 and its pathophysiological role after spinal cord injury. J Mol Neurosci 49:347-59 |
| Montiel-Gonzalez, Maria Fernanda; Vallecillo-Viejo, Isabel; Yudowski, Guillermo A et al. (2013) Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing. Proc Natl Acad Sci U S A 110:18285-90 |
| Santiago-Rodriguez, Tasha M; Rivera, Jessica I; Coradin, Mariel et al. (2013) Antibiotic-resistance and virulence genes in Enterococcus isolated from tropical recreational waters. J Water Health 11:387-96 |
| Pantoja-Feliciano, Ida Gisela; Clemente, Jose C; Costello, Elizabeth K et al. (2013) Biphasic assembly of the murine intestinal microbiota during early development. ISME J 7:1112-5 |
| Garrett, Sandra C; Rosenthal, Joshua J C (2012) A role for A-to-I RNA editing in temperature adaptation. Physiology (Bethesda) 27:362-9 |
| Garrett, Sandra; Rosenthal, Joshua J C (2012) RNA editing underlies temperature adaptation in K+ channels from polar octopuses. Science 335:848-51 |
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