Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54NS041073-09
Application #
7931905
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
9
Fiscal Year
2009
Total Cost
$585,950
Indirect Cost
Name
Hunter College
Department
Type
DUNS #
620127915
City
New York
State
NY
Country
United States
Zip Code
10065
Kiprowska, Magdalena J; Stepanova, Anna; Todaro, Dustin R et al. (2017) Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis 1863:1157-1170
He, Huifang; Deng, Kangwen; Siddiq, Mustafa M et al. (2016) Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5. J Neurosci 36:3079-91
Siddiq, Mustafa M; Hannila, Sari S; Carmel, Jason B et al. (2015) Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System. J Biol Chem 290:16343-56
Shivers, Kai-Yvonne; Nikolopoulou, Anastasia; Machlovi, Saima Ishaq et al. (2014) PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2. Biochim Biophys Acta 1842:1707-19
Huang, Qian; Wang, Hu; Perry, Seth W et al. (2013) Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons. J Biol Chem 288:12161-74
Huang, He; Wang, Hu; Figueiredo-Pereira, Maria E (2013) Regulating the ubiquitin/proteasome pathway via cAMP-signaling: neuroprotective potential. Cell Biochem Biophys 67:55-66
Hannila, Sari S; Siddiq, Mustafa M; Carmel, Jason B et al. (2013) Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-? signaling protein Smad2. J Neurosci 33:5138-51
Myeku, Natura; Wang, Hu; Figueiredo-Pereira, Maria E (2012) cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons. Neurosci Lett 527:126-31
Metcalfe, M J; Huang, Q; Figueiredo-Pereira, M E (2012) Coordination between proteasome impairment and caspase activation leading to TAU pathology: neuroprotection by cAMP. Cell Death Dis 3:e326
Myeku, Natura; Figueiredo-Pereira, Maria E (2011) Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. J Biol Chem 286:22426-40

Showing the most recent 10 out of 56 publications