The goal of the Cell and Molecular Core is'to provide sensitive and powerful molecular tools and models to facilitate projects for members of the Neuroscience Institute. The Cell and Molecular Core will provide support and services that include GeneChip expression analysis, Real Time measurements of PCR reactions, Genetic reporter systems (Dual-Luciferase Reporter Assay System), and other state-of-the-art approaches to facilitate research by neuroscience investigators. The Cell and Molecular Biology Core facility will also provide technical expertise and training to investigators of the Institute in a number of essential techniques. By providing these services, as well as basic reagents, the Core will facilitate progress towards each project proposed by the investigators in the Neuroscience Institute. During the previous funding cycle, the Core has been highly successful in assisting investigators with generating data for publication in peerreviewed journals and for securing funding for ongoing research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54NS060659-05
Application #
8377070
Study Section
Special Emphasis Panel (ZNS1-SRB-R)
Project Start
Project End
2014-05-31
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
5
Fiscal Year
2012
Total Cost
$49,401
Indirect Cost
$15,136
Name
Morehouse School of Medicine
Department
Type
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
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Ehlen, J Christopher; Brager, Allison J; Baggs, Julie et al. (2017) Bmal1 function in skeletal muscle regulates sleep. Elife 6:
Reynolds, James P; Jimenez-Mateos, Eva M; Cao, Li et al. (2017) Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury. Neurochem Res 42:2033-2054
Zhou, An (2016) Proteomics in stroke research: potentials of the nascent proteomics. J Investig Med 64:1236-1240
Simmons, Lauren J; Surles-Zeigler, Monique C; Li, Yonggang et al. (2016) Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. J Neuroinflammation 13:237
White, Todd E; Surles-Zeigler, Monique C; Ford, Gregory D et al. (2016) Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury. BMC Genomics 17:130
Meller, Robert; Pearson, Andrea; Simon, Roger P (2015) Dynamic changes in DNA methylation in ischemic tolerance. Front Neurol 6:102
Reynolds, James P; Miller-Delaney, Suzanne F C; Jimenez-Mateos, Eva M et al. (2015) Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning. Front Neurol 6:46
Evans, Jennifer A; Suen, Ting-Chung; Callif, Ben L et al. (2015) Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body. BMC Biol 13:43

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