The Discovering Healthcare innovations to Address Disparities in Stroke (DIADS) program is a collaboration between Kaiser Permanente Northern California (KPNC) and the University of California, San Francisco (UCSF). The program consists of a pragmatic randomized controlled trial that includes a culturally tailored Diet and Lifestyle and a clinically delivered hypertension control intervention.(Project I), an observational cohort study that will examine racial disparities in ischemic stroke and atherosclerotic risk factors in the young (Project 11), and four Core projects designed to support the research projects in KPNC and rapidly and effectively disseminate information to the Alameda County community health clinics and train healthcare professionals and community clinical leaders in effective implementation of clinically-based interventions addressing primary prevention of stroke in African Americans. The Administrative Core will be located at the Kaiser Permanente Northern California Division of Research (KPNC DOR). Stephen Sidney, MD, MPH is the SPIRP Director and has overall administrative and scientific responsibility for overseeing program. Noelle Blick MPH, will lead the Administrative Core. She has 15 years experience in developing initiatives and managing collaborations with diverse partners. Her leadership roles and expertise in research department operations, grants and contracts (federal, state and biotech) financial management, compliance and IRB include regional and national positions with Kaiser Permanente. A strong and effective Administrative Core is essential to the success of the DIADS program. The Administrative Core (DOR) and will be responsible for managing coordination, communication resources and integration, monitoring progress of the aims, expediting necessary contracts, agreements and IRB documents and developing and implementing the data sharing plan across all Projects and Cores and will coordinate with Program Advisory Committee (PAC), the Executive Committee and with the funding institution and research partner, the National Institute on Neurological Disorders and Stroke (NINDS).

Public Health Relevance

DIADS is a complex project that requires vision, infrastructure and significant coordination of activities between the lead institution, (KPNC) and the partnering research institution (UCSF). In addition, we will coordinate with the clinical services of KPNC in its East Bay Service Area, the community clinics of Alameda County by partnering with the Alameda County Public Health Department and the Health Care Services Agency, the General Medical Clinic at San Francisco General Hospital, and with the funding institution and research partner, the National Institute on Neurological Disorders and Stroke (NINDS).

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54NS081760-03
Application #
8727681
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Kaiser Foundation Research Institute
Department
Type
DUNS #
City
Oakland
State
CA
Country
United States
Zip Code
94612
Mayeda, Elizabeth Rose; Filshtein, Teresa J; Tripodis, Yorghos et al. (2018) Does selective survival before study enrolment attenuate estimated effects of education on rate of cognitive decline in older adults? A simulation approach for quantifying survival bias in life course epidemiology. Int J Epidemiol 47:1507-1517
Fontil, Valy; Lyles, Courtney R; Schillinger, Dean et al. (2018) Safety-net institutions in the US grapple with new cholesterol treatment guidelines: a qualitative analysis from the PHoENIX Network. Risk Manag Healthc Policy 11:99-108
Fontil, Valy; Gupta, Reena; Moise, Nathalie et al. (2018) Adapting and Evaluating a Health System Intervention From Kaiser Permanente to Improve Hypertension Management and Control in a Large Network of Safety-Net Clinics. Circ Cardiovasc Qual Outcomes 11:e004386
Mayeda, Elizabeth Rose; Banack, Hailey R; Bibbins-Domingo, Kirsten et al. (2018) Can Survival Bias Explain the Age Attenuation of Racial Inequalities in Stroke Incidence?: A Simulation Study. Epidemiology 29:525-532
Mayeda, Elizabeth R; Glymour, M Maria; Quesenberry Jr, Charles P et al. (2017) Heterogeneity in 14-year Dementia Incidence Between Asian American Subgroups. Alzheimer Dis Assoc Disord 31:181-186
Fontil, Valy; Bibbins-Domingo, Kirsten; Nguyen, Oanh Kieu et al. (2017) Management of Hypertension in Primary Care Safety-Net Clinics in the United States: A Comparison of Community Health Centers and Private Physicians' Offices. Health Serv Res 52:807-825
Mayeda, Elizabeth R; Glymour, M Maria; Quesenberry, Charles P et al. (2017) Survival after dementia diagnosis in five racial/ethnic groups. Alzheimers Dement 13:761-769
Vasudeva, Eshan; Moise, Nathalie; Huang, Chen et al. (2016) Comparative Cost-Effectiveness of Hypertension Treatment in Non-Hispanic Blacks and Whites According to 2014 Guidelines: A Modeling Study. Am J Hypertens 29:1195-205
Odden, Michelle C; Moran, Andrew E; Coxson, Pamela G et al. (2016) Gait Speed as a Guide for Blood Pressure Targets in Older Adults: A Modeling Study. J Am Geriatr Soc 64:1015-23
Moran, Andrew E; Odden, Michelle C; Thanataveerat, Anusorn et al. (2015) Cost-effectiveness of hypertension therapy according to 2014 guidelines. N Engl J Med 372:447-55

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