This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall objective is to develop the infrastructure, equipment and expertise to understand the pathogenesis and treatment of metabolic diseases such as diabetes, obesity, hypercholesterolemia and endocrine regulatory mechanisms.
The specific aims of this Core are to: 1. Provide centralized access via a laboratory to facilities and equipment for body composition assessment in humans; 2. Enhance research capabilities and competitiveness of Drew investigators currently engaged on metabolic research; and 3. Facilitate recruitment of investigators with expertise in state-of-the art metabolic and body composition methodology, as well as a commitment to diabetes and metabolic research. 4. Increase the body of knowledge and research activity (grant submissions and procurement, presentations and publications) in the area of diabetes and metabolic disorders as related to improving the health care of women, ethnic/racial minorities and other disadvantaged populations. Members of this Core will continue independent research and apply for grants to help expand capacity. The Body Composition and Metabolic Core will: 1) Conduct independent research; 2) provide nutritional counseling and assessment; 3) provide anthropometry; 4) provide bioelectrical impedance; 5) provide DEXA scan; 6) quantitate body composition by deuterium labeled water and sodium bromide; 7) provide muscle size assessment by MRI scan; 8) provide measurement of abdominal fat by MRI; and 9) provide underwater weights.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR014616-08
Application #
7380857
Study Section
Special Emphasis Panel (ZRR1-RI-1 (01))
Project Start
2006-08-01
Project End
2007-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
8
Fiscal Year
2006
Total Cost
$199,559
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
Ren, Xiuhai; Lutfy, Kabirullah; Mangubat, Michael et al. (2013) Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes 2013:764742
Tweed, Jesse Oliver; Hsia, Stanley H; Lutfy, Kabirullah et al. (2012) The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab 23:334-42
Hsia, Stanley H (2011) Insulin glargine compared to NPH among insulin-naïve, U.S. inner city, ethnic minority type 2 diabetic patients. Diabetes Res Clin Pract 91:293-9
Hsia, Stanley H; Navar, Maria D; Duran, Petra et al. (2011) Sitagliptin compared with thiazolidinediones as a third-line oral antihyperglycemic agent in type 2 diabetes mellitus. Endocr Pract 17:691-8
Calderón, José Luis; Bazargan, Mohsen; Sangasubana, Nisaratana et al. (2010) A comparison of two educational methods on immigrant Latinas breast cancer knowledge and screening behaviors. J Health Care Poor Underserved 21:76-90
Davidson, Mayer B; Schriger, David L (2010) Effect of age and race/ethnicity on HbA1c levels in people without known diabetes mellitus: implications for the diagnosis of diabetes. Diabetes Res Clin Pract 87:415-21
Jones, Loretta; Lu, Michael C; Lucas-Wright, Aziza et al. (2010) One Hundred Intentional Acts of Kindness toward a Pregnant Woman: building reproductive social capital in Los Angeles. Ethn Dis 20:S2-36-40
Kilimnik, German; Kim, Abraham; Steiner, Donald F et al. (2010) Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic ?-cells in mouse models of ß-cell regeneration. Islets 2:149-55
Anghel, A; Jamieson, C A M; Ren, X et al. (2010) Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake. Neuroscience 167:554-66
Chen, John; Patel, Roshni; Friedman, Theodore C et al. (2010) The Behavioral and Pharmacological Actions of NMDA Receptor Antagonism are Conserved in Zebrafish Larvae. Int J Comp Psychol 23:82-90

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