Abstract

This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Dr. Boeke has developed and will administer the management plan for this TCNP. The TCNP management plan is centered on the existing organizational structure of our new HiT Center www.hopkinsmedicine.org/IBBS/HiT, which already has a strong proteomics component and was in fact expressly designed to facilitate the type of work embodied in the TCNP.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR020839-05
Application #
7724697
Study Section
Special Emphasis Panel (ZRG1-BST-D (55))
Project Start
2008-08-01
Project End
2009-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
5
Fiscal Year
2008
Total Cost
$305,398
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Uzoma, Ijeoma; Hu, Jianfei; Cox, Eric et al. (2018) Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration. Mol Cell Proteomics 17:871-888
Cox, Eric; Hwang, Woochang; Uzoma, Ijeoma et al. (2017) Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex. Mol Cell Proteomics 16:812-823
Newman, Heather A; Meluh, Pamela B; Lu, Jian et al. (2017) A high throughput mutagenic analysis of yeast sumo structure and function. PLoS Genet 13:e1006612
Noren, David P; Chou, Wesley H; Lee, Sung Hoon et al. (2016) Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Sci Signal 9:ra20
Sabari, Benjamin R; Tang, Zhanyun; Huang, He et al. (2015) Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation. Mol Cell 58:203-15
Wu, Zhixiang; Cheng, Zhongyi; Sun, Mingwei et al. (2015) A chemical proteomics approach for global analysis of lysine monomethylome profiling. Mol Cell Proteomics 14:329-39
Hu, Jianfei; Neiswinger, Johnathan; Zhang, Jin et al. (2015) Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction. PLoS Comput Biol 11:e1004508
Liu, Shuang; Zhang, Hongyan; Dai, Jun et al. (2015) Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach. MAbs 7:110-9
Cubeñas-Potts, Caelin; Srikumar, Tharan; Lee, Christine et al. (2015) Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics 15:763-72
Zhong, Jun; Martinez, Marissa; Sengupta, Srona et al. (2015) Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway. Proteomics 15:591-607

Showing the most recent 10 out of 219 publications