This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff.
The specific aims for our study have not been modified at this time. Our long-term objective is still to identify and eliminate factors that contribute to racial/ethnic disparities in mental health treatment. Toward that goal, the proposed study is designed to identify the main predictors of mental health and medical treatment linkage and engagement in an African American population with severe and persistent mental illness. The central hypothesis of this proposal is that specific attitudinal, clinical, and social factors are highly correlated with linkage and engagement with mental health and medical treatment. By identifying these factors, our goal is to design targeted interventions to improve negative factors and enhance positive factors that contribute to overall linkage and engagement in mental health and medical treatment in racial/ethnic minority populations. Regarding each specific aim, we are beginning to make progress toward each of these goals.
Specific Aim 1 : To determine the predictors of mental health treatment linkage and engagement among low-income, socially disadvantaged, predominantly African American individuals with severe mental illness.
Specific Aim 2 : To determine the predictors of general medical services treatment linkage among low-income, socially disadvantaged, predominantly African American individuals with severe mental illness.
Specific Aim 3 : To determine the association between successful linkage with mental health services and general medical services. We anticipate an analysis of individuals with severe mental illness and their rates of ongoing linkage and engagement in mental health and medical treatment will help to improve overall treatment of individuals with severe mental illness. Because we are focusing this study on a predominantly African American population, we hope to gain greater understanding that will serve to eliminate racial/ethnic disparities associated with mental health and medical treatment.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR026137-03
Application #
8359906
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2011-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
3
Fiscal Year
2011
Total Cost
$124,719
Indirect Cost
Name
Morehouse School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Piano, Ilaria; Baba, Kenkichi; Claudia Gargini et al. (2018) Heteromeric MT1/MT2 melatonin receptors modulate the scotopic electroretinogram via PKC? in mice. Exp Eye Res 177:50-54
Owino, Sharon; Sánchez-Bretaño, Aida; Tchio, Cynthia et al. (2018) Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity. J Pineal Res 64:
Augello, Catherine J; Noll, Jessica M; Distel, Timothy J et al. (2018) Identification of novel blood biomarker panels to detect ischemic stroke in patients and their responsiveness to therapeutic intervention. Brain Res 1698:161-169
Ofili, Elizabeth O; Pemu, Priscilla E; Quarshie, Alexander et al. (2018) DEMOCRATIZING DISCOVERY HEALTH WITH N=Me. Trans Am Clin Climatol Assoc 129:215-234
Sánchez-Bretaño, Aída; Baba, Kenkichi; Janjua, Uzair et al. (2017) Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3. Mol Vis 23:844-852
Laurent, Virgine; Sengupta, Anamika; Sánchez-Bretaño, Aída et al. (2017) Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium. Exp Eye Res 165:90-95
Chen, Xiaoming; Cobbs, Alyssa; George, Jasmine et al. (2017) Endocytosis of Albumin Induces Matrix Metalloproteinase-9 by Activating the ERK Signaling Pathway in Renal Tubule Epithelial Cells. Int J Mol Sci 18:
Simmons, Lauren J; Surles-Zeigler, Monique C; Li, Yonggang et al. (2016) Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. J Neuroinflammation 13:237
Zhao, Xueying; Jiang, Chen; Olufade, Rebecca et al. (2016) Kidney Injury Molecule-1 Enhances Endocytosis of Albumin in Renal Proximal Tubular Cells. J Cell Physiol 231:896-907
Jockers, Ralf; Delagrange, Philippe; Dubocovich, Margarita L et al. (2016) Update on melatonin receptors: IUPHAR Review 20. Br J Pharmacol 173:2702-25

Showing the most recent 10 out of 71 publications