The Overarching Goal of the Indiana Clinical and Translational Science Institute (CTSI) is to transformthe Darticipating institutions to create an environment that facilitates the conduct of biomedical research. Mission Statement: """"""""To increase translational biomedical research and improve the health of the people of Indiana and beyond."""""""" To this end, we have developed new mechanisms to acceleratetranslational research, including enhanced educational programs to train translational researchers,a newly designed community engagement activity to produce effective and bidirectional community partnerships, streamlining of all available research infra- structure to acceleratetranslational projects,and partnering with commercial and philanthropic organizations in Indiana. Throughout all of these efforts runs the critical link of our medical informatics program, enabling all parties to interact in a facile and responsive and prompt manner. Thus, the Indiana CTSI brings together the resourcesof an entire state. In short, it will provide to the national network of CTSAs: A true statewide laboratory to experiment with innovative methods aimed at transforming researchin biomedical sciences, health economy, health care delivery, and health policy. The 5 Specific goals of the Indiana CTSI: I. Create Translational Research Acceleration Programsand Support Pilot Projects by providing investigators and consumers with strategic leadership and mentorship to identify, evaluate, and support innovative and important pilot researchat each step of the translational cycle. . Train a new cadre of Translational Researchersby strengthening existing programs and creating new ones to educate trainees and engage faculty in the translational sciences. HI. Foster Robust Community Engagement by creating novel programs with bidirectional participation (i.e., from academia to the community and back again), such as the Indiana Community Health Enhancement Program (CHEP) and pilot programs in Health Econmics, and Rural and Global Health. IV. Build Facile and Comprehensive Research Resourcesand Technologies by transforming the existing and new research infrastructure into innovative programssuch as the Participant and Clinical Interaction Resources (PCIR), Translational Technology Resources(TTR). Research Ethics, Biostatistics and Design Program (BDP), and uniquely, biomedical engineering and bio-nanotechnology to facilitate health research. V. Leverage the Resources of the Greater Indiana Community by connecting to a broad array of resources from multiple partner institutions throughout the state to realize the full potential of the Indiana CTSI.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Linked Specialized Center Cooperative Agreement (UL1)
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Study Section
Special Emphasis Panel (ZRR1-SRC (99))
Program Officer
Rosenblum, Daniel
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Indiana University-Purdue University at Indianapolis
Schools of Medicine
United States
Zip Code
Dakhoul, Lara; Ghabril, Marwan; Gu, Jiezhun et al. (2018) Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers. Clin Gastroenterol Hepatol 16:722-729.e2
Maatman, Benjamin T; Schmeisser, Glen; Kreutz, Rolf P (2018) Fibrin Clot Strength in Patients with Diabetes Mellitus Measured by Thrombelastography. J Diabetes Res 2018:4543065
Ma, Ruoyun E; Ward, Eric J; Yeh, Chien-Lin et al. (2018) Thalamic GABA levels and occupational manganese neurotoxicity: Association with exposure levels and brain MRI. Neurotoxicology 64:30-42
Ipe, Joseph; Collins, Kimberly S; Hao, Yangyang et al. (2018) PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites. Front Genet 9:219
Zhao, Shu; Wang, Xiaoting; Gao, Xiang et al. (2018) Delayed and progressive damages to juvenile mice after moderate traumatic brain injury. Sci Rep 8:7339
Stremke, Elizabeth R; McCabe, Linda D; McCabe, George P et al. (2018) Twenty-Four-Hour Urine Phosphorus as a Biomarker of Dietary Phosphorus Intake and Absorption in CKD: A Secondary Analysis from a Controlled Diet Balance Study. Clin J Am Soc Nephrol 13:1002-1012
Macy, Jonathan T; Moser, Elizabeth A S; Hirsh, Adam T et al. (2018) Factors associated with seeking preventive dental care: an integrative model exploration of behaviors in Mexican immigrants in Midwest America. BMC Oral Health 18:37
Robertson, Michael J; Stamatkin, Christopher W; Pelloso, David et al. (2018) A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma. J Immunother 41:151-157
Church, Rachel J; Kullak-Ublick, Gerd A; Aubrecht, Jiri et al. (2018) Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort. Hepatology :
Guthrie, Katherine A; Larson, Joseph C; Ensrud, Kristine E et al. (2018) Effects of Pharmacologic and Nonpharmacologic Interventions on Insomnia Symptoms and Self-reported Sleep Quality in Women With Hot Flashes: A Pooled Analysis of Individual Participant Data From Four MsFLASH Trials. Sleep 41:

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