The goal of the South Carolina Clinical and Translational Research Institute (SCTR) is to create a sustainable home at the Medical University of South Carolina (MUSC) to advance clinical and translational research as a distinct discipline and facilitate collaboration across multiple disciplines. The overall approach focuses on: (1) implementing important advances in biomedical science to create opportunities for discovery, (2) removing barriers to facilitate the linkage of knowledge, experience and expertise across disciplinary boundaries, (3) providing training and mentoring experiences to enhance the pipeline for clinical and translational researchers with diverse training and backgrounds, and (4) fostering community engagement with a rapidly growing statewide population that is underserved by many systems to improve their participation and health outcomes. MUSC has long-standing experience leading successful clinical and translational research efforts that span the state. It is the leading state institution in extramurally funded research activities and has a rich research training portfolio. SCTR was established in 2007 with the vision that it would be the """"""""agent of change"""""""" in transforming the research culture at MUSC and statewide via strong relationships with academic and community-based affiliates. Great progress has already been made including the development of an institutional K12 Career Development Program in Clinical and Translational Research, implementation of a pilot project program that funded 29 projects in the first two competitive rounds, and establishment of a robust collaboration with the NIH-funded CTSA at Vanderbilt University for assistance in the SCTR Biomedical Informatics Program. Joining the national CTSA Consortium will accelerate progress by further facilitating (1) development and interoperability of biomedical informatics systems, (2) active exchange of best processes and best practices in evidence-based medicine and community engagement, (3) advancement of clinical and translational science as a discipline and career path;and (4) shared knowledge, experience and collective influence in setting regional and national research agendas and health policy designed to generate the transformative results envisioned by the NIH Roadmap.

Public Health Relevance

SCTR will bring together scientists, clinicians and the lay community to address diseases that commonly impact the citizens of South Carolina. SCTR will coordinate resources and expertise statewide in efficient, innovative approaches to research. Through SCTR, a new generation of researchers will be trained to work across multiple disciplines in collaboration with community members so that scientific discovery is relevant and ranirilv tran.'slateri tn frnnt-linfi trfiatmfint .settinn.'s for maximum imnant nn health niitcnmes

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1RR029882-03
Application #
8092542
Study Section
Special Emphasis Panel (ZRR1-CR-1 (02))
Program Officer
Purucker, Mary E
Project Start
2009-07-14
Project End
2014-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
3
Fiscal Year
2011
Total Cost
$3,312,909
Indirect Cost
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Li, Chao; D'Agostino Jr, Ralph B; Dabelea, Dana et al. (2018) Longitudinal association between eating frequency and hemoglobin A1c and serum lipids in diabetes in the SEARCH for Diabetes in Youth study. Pediatr Diabetes :
Chiarello, Christine; Vaden Jr, Kenneth I; Eckert, Mark A (2018) Orthographic influence on spoken word identification: Behavioral and fMRI evidence. Neuropsychologia 111:103-111
Faith, Trevor D; Flournoy-Floyd, Minnjuan; Ortiz, Kasim et al. (2018) My life with lupus: contextual responses of African-American women with systemic lupus participating in a peer mentoring intervention to improve disease self-management. BMJ Open 8:e022701
Patel, Zubin; Lu, Xiaoming; Miller, Daniel et al. (2018) A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet :
Putterman, Chaim; Pisetsky, David S; Petri, Michelle et al. (2018) The SLE-key test serological signature: new insights into the course of lupus. Rheumatology (Oxford) 57:1632-1640
Ruiz, Daniel; Oates, Jim C; Kamen, Diane L (2018) Antiphospholipid Antibodies and Heart Valve Disease in Systemic Lupus Erythematosus. Am J Med Sci 355:293-298
Germeroth, Lisa J; Baker, Nathaniel L; Saladin, Michael E (2018) Intolerance for smoking abstinence among nicotine-deprived, treatment-seeking smokers. Addict Behav 84:13-19
Fair, Patricia A; White, Natasha D; Wolf, Beth et al. (2018) Persistent organic pollutants in fish from Charleston Harbor and tributaries, South Carolina, United States: A risk assessment. Environ Res 167:598-613
Sieverdes, John C; Treiber, Frank A; Mueller, Martina et al. (2018) Living Organ Video Educated Donors Program for Kidney Transplant-eligible African Americans to Approach Potential Donors: A Proof of Concept. Transplant Direct 4:e357
Williams, Edith M; Hyer, J Madison; Viswanathan, Ramakrishnan et al. (2018) Peer-to-Peer Mentoring for African American Women With Lupus: A Feasibility Pilot. Arthritis Care Res (Hoboken) 70:908-917

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