We have established the San Diego Clinical and Translational Research Institute (San Diego CTRI), with its hublocated at the University of California, San Diego (UCSD). This regional center contains two universities (UCSDand San Diego State University), 4 biomedical research institutes (Salk Inst., Burnham Inst., J. Craig Venter Inst.,and La Jolla Inst, for Allergy and Immunology), and 3 academic hospitals (UCSD Medical Center, VA Hospitaland Rady Children's Hospital), one community health sen/ice (Palomar Pomerado Health) and 2 specializedresources~the San Diego Supercomputer Center and the California Inst, for Telecommunications andInformation Technology. The CTSA program encompasses 3 health sciences professional schools (Medicine,Pharmacy, Nursing), nine clinical research PhD programs, and a Masters program in Advanced Clinical Studies.The program goals are to: 1) Provide an academic home for the discipline of clinical and translational science; 2)Establish an integrated educational pipeline to train and support clinical and translational scientists; 3) Develop arobust clinical research infrastructure that replaces silos with integrated research; 4) Enhance bioinformaticscapabilities that leverage unique UCSD resources; 5) Develop novel technologies to improve research such asbiomarker and imaging; 6) Form a Translational Research Alliance with research institutes and industry; 7) Forma Community Alliance with community physicians and the general public to translate scientific discoveries intobest practices, increase research into health care disparities, and involve the general public in biomedicalscience. The CTSA program will provide the resources to develop the discipline of clinical and translationalresearch. Through the San Diego CTRI, the educational pipeline to train the next generation of clinical andtranslational scientists will be enhanced. A new K12 program, an expanded K30 program, and the integration ofnew PhD graduate programs in clinical research highlight the proposed educational plan. The CTRI will transformeducation in clinical and translational science by coordinating disparate programs, providing breadth of educationfrom high school through pre-doctoral students and providing training to post-doctoral fellows and faculty. TheInstitute will also transform the conduct of clinical research by providing guidance and support from initialplanning through data analysis and sharing. The new structure will foster development of novel technologies tofacilitate clinical research and provide support for the services and resources necessary to conduct clinicalinvestigation. We will place special emphasis on several areas of strength such as imaging, biomarkers,community outreach, and the translation of basic science discoveries to clinical science.

Public Health Relevance

The San Diego Clinical Translational Research Institute will transform the clinical research by providing guidanceand support from initial planning through data analysis and sharing. It will provide an educational pipeline to trainthe next generation of clinical and translational scientists and involve the community in setting the direction andpriorities of the organization. The Institute will foster development of novel technologies that facilitate clinicalresearch, and provide support for the services needed to conduct clinical investigation and improve health.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Linked Specialized Center Cooperative Agreement (UL1)
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Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Merchant, Carol
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University of California San Diego
Internal Medicine/Medicine
Schools of Medicine
La Jolla
United States
Zip Code
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