The Michigan Institute for Clinical & Health Research (MICHR) is a catalytic hub that significantly impacts the translation of investigative science into innovative improvements in clinical care and health policy. Our objective is to empower researchers and research communities within and outside the University of Michigan (U-M), creating a positive impact on health across local, regional, national, and global scales. We will achieve this objective through the following overarching specific aims: 1) Innovate and implement effective educational approaches to developing a skilled and diverse translational research workforce; 2) Catalyze effective research with community partnerships to accelerate the translation of breakthroughs that benefit society; 3) Promote clinical and translational research across translational phases and across the lifespan; 4) Advance research methods and processes that enable higher quality clinical and translational research; 5) Develop, demonstrate, and disseminate informatics innovations that facilitate the translation of biomedical discoveries to health impact. MICHR aspires to have a unique, substantial, measurable, and recognizable impact on U-M and the health of our communities. In order to achieve this with efficiency, we have critically evaluated pre- existing strengths and emerging opportunities across the institutional research landscape. MICHR will enhance and develop partnerships with major research and regulatory units on campus to develop an efficient pipeline that accelerates the translation and implementation of discoveries while also promoting cross-cutting signature initiatives that engage research and community members from all phases of translation.

Public Health Relevance

The Michigan Institute for Clinical & Health Research (MICHR) is a catalytic hub that significantly impacts the translation of investigative science into innovative improvements in clinical care and health policy. Our objective is to empower researchers and research communities within and outside the University of Michigan, creating a positive impact on health across local, regional, national, and global scales. MICHR will build on a decade of enabling and enhancing clinical and translational research. We expect expanded positive impact as we develop, demonstrate, and disseminate innovative and highly integrated initiatives across our institute, the University of Michigan campus, surrounding communities, and the Clinical Translational Science Awards consortium.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR002240-05
Application #
10116514
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Chang, Soju
Project Start
2017-06-01
Project End
2022-02-28
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
5
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Huang, Wei; Wang, Lu; Li, Jianping et al. (2018) Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations. Am J Hypertens 31:590-599
Gaies, Michael; Werho, David K; Zhang, Wenying et al. (2018) Duration of Postoperative Mechanical Ventilation as a Quality Metric for Pediatric Cardiac Surgical Programs. Ann Thorac Surg 105:615-621
Mendiratta-Lala, Mishal; Gu, Everett; Owen, Dawn et al. (2018) Imaging Findings Within the First 12 Months of Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys 102:1063-1069
Sun, Yihan; Kim, Jae Hyun; Vangipuram, Kiran et al. (2018) Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy. Breast Cancer Res Treat 171:657-666
Rosenblum, Katherine; Lawler, Jamie; Alfafara, Emily et al. (2018) Improving Maternal Representations in High-Risk Mothers: A Randomized, Controlled Trial of the Mom Power Parenting Intervention. Child Psychiatry Hum Dev 49:372-384
Fontana, M; Eckert, G J; Keels, M A et al. (2018) Fluoride Use in Health Care Settings: Association with Children's Caries Risk. Adv Dent Res 29:24-34
Eisenberg, Marisa C; Campredon, Lora P; Brouwer, Andrew F et al. (2018) Dynamics and Determinants of HPV Infection: The Michigan HPV and Oropharyngeal Cancer (M-HOC) Study. BMJ Open 8:e021618
Zaikos, Thomas D; Painter, Mark M; Sebastian Kettinger, Nadia T et al. (2018) Class 1-Selective Histone Deacetylase (HDAC) Inhibitors Enhance HIV Latency Reversal while Preserving the Activity of HDAC Isoforms Necessary for Maximal HIV Gene Expression. J Virol 92:
Feng, Mary; Suresh, Krithika; Schipper, Matthew J et al. (2018) Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial. JAMA Oncol 4:40-47
Dakhoul, Lara; Ghabril, Marwan; Gu, Jiezhun et al. (2018) Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers. Clin Gastroenterol Hepatol 16:722-729.e2

Showing the most recent 10 out of 207 publications