Abstract

During the past year, our research included studies of: (1) neurobiology and behaviors that laboratory work has shown are correlated with excessive alcohol consumption, including aggression, impulsivity, and reduced affiliative social behavior; (2) low CSF 5-HIAA concentrations, aggression, and premature mortality; (3) traits maintaining the low CSF 5-HIAA genotype in the gene pool; (4) studies were continued on 49 adolescent females that were removed from the island to investigate the role of immune functioning, temperament, psychosocial health, and competent social behavior; and (5) new technologies have been developed, including telemetry for assessment of diurnal activity, and new traps for capture of subjects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Intramural Research (Z01)
Project #
1Z01AA000079-02
Application #
2333274
Study Section
Special Emphasis Panel (LCS)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
National Institute on Alcohol Abuse and Alcoholism
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Flory, G S; Chen, S A; Woltz, L A et al. (2006) A computerized apparatus designed to automatically dispense, measure, and record alcohol consumption by individual members of a rhesus macaque social group: trait-like drinking across social- and single-cage conditions. Methods 38:178-84
Jaffe, Benjamin D; Evans, Theodore A; Howell, Sue et al. (2006) Left versus right nipple preference in free-ranging infant rhesus macaques (Macaca mulatta). Dev Psychobiol 48:266-72
Kumar, Rakesh; Perez-Casanova, Antonio E; Tirado, Grissell et al. (2005) Increased viral replication in simian immunodeficiency virus/simian-HIV-infected macaques with self-administering model of chronic alcohol consumption. J Acquir Immune Defic Syndr 39:386-90
Anderson, George M; Barr, Christina S; Lindell, Stephen et al. (2005) Time course of the effects of the serotonin-selective reuptake inhibitor sertraline on central and peripheral serotonin neurochemistry in the rhesus monkey. Psychopharmacology (Berl) 178:339-46
Cleveland, Allison; Westergaard, Gregory C; Trenkle, Marisa K et al. (2004) Physiological predictors of reproductive outcome and mother-infant behaviors in captive rhesus macaque females (Macaca mulatta). Neuropsychopharmacology 29:901-10
Westergaard, G C; Chavanne, T J; Houser, L et al. (2004) Biobehavioural correlates of hand preference in free-ranging female primates. Laterality 9:267-85
Heinz, A; Jones, D W; Zajicek, K et al. (2004) Depletion and restoration of endogenous monoamines affects beta-CIT binding to serotonin but not dopamine transporters in non-human primates. J Neural Transm Suppl :29-38
Westergaard, Gregory C; Suomi, Stephen J; Chavanne, Tara J et al. (2003) Physiological correlates of aggression and impulsivity in free-ranging female primates. Neuropsychopharmacology 28:1045-55
Westergaard, G C; Cleveland, A; Trenkle, M K et al. (2003) CSF 5-HIAA concentration as an early screening tool for predicting significant life history outcomes in female specific-pathogen-free (SPF) rhesus macaques (Macaca mulatta) maintained in captive breeding groups. J Med Primatol 32:95-104
Westergaard, G C; Chavanne, T J; Lussier, I D et al. (2003) Left-handedness is correlated with CSF monoamine metabolite and plasma cortisol concentrations, and with impaired sociality, in free-ranging adult male rhesus macaques (Macaca mulatta). Laterality 8:169-87

Showing the most recent 10 out of 16 publications