Abstract

NMR spectroscopy is currently being used at the NIA to study the phosphorus metabolism of peripheral muscle. Age-related, hormone related and exercise-related effects are under investigation. Methodologic studies to further develop kinetic and spin-lattice relaxation time measurement methodology are also being actively pursued. Connective tissue work has been initiated.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000381-06
Application #
2447732
Study Section
Special Emphasis Panel (LCMB)
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
National Institute on Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Bouhrara, Mustapha; Bonny, Jean-Marie; Ashinsky, Beth G et al. (2017) Noise Estimation and Reduction in Magnetic Resonance Imaging Using a New Multispectral Nonlocal Maximum-likelihood Filter. IEEE Trans Med Imaging 36:181-193
Ashinsky, Beth G; Bouhrara, Mustapha; Coletta, Christopher E et al. (2017) Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative. J Orthop Res 35:2243-2250
Cameron, Donnie; Bouhrara, Mustapha; Reiter, David A et al. (2017) The effect of noise and lipid signals on determination of Gaussian and non-Gaussian diffusion parameters in skeletal muscle. NMR Biomed 30:
Bouhrara, Mustapha; Reiter, David A; Spencer, Richard G (2015) Bayesian analysis of transverse signal decay with application to human brain. Magn Reson Med 74:785-802
Irrechukwu, Onyi N; Thaer, Sarah Von; Frank, Eliot H et al. (2014) Prediction of cartilage compressive modulus using multiexponential analysis of T(2) relaxation data and support vector regression. NMR Biomed 27:468-77
Reiter, David A; Roque, Remigio A; Lin, Ping-Chang et al. (2011) Improved specificity of cartilage matrix evaluation using multiexponential transverse relaxation analysis applied to pathomimetically degraded cartilage. NMR Biomed 24:1286-94
Lin, Ping-Chang; Reiter, David A; Spencer, Richard G (2009) Classification of degraded cartilage through multiparametric MRI analysis. J Magn Reson 201:61-71
Ramaswamy, Sharan; Wang, Dong-An; Fishbein, Kenneth W et al. (2006) An analysis of the integration between articular cartilage and nondegradable hydrogel using magnetic resonance imaging. J Biomed Mater Res B Appl Biomater 77:144-8
Spencer, Richard G; Fishbein, Kenneth W; Cheng, Aiwu et al. (2006) Compatibility of Gd-DTPA perfusion and histologic studies of the brain. Magn Reson Imaging 24:27-31
Canuto, Holly C; Oliveira, Miguel L R; Fishbein, Kenneth W et al. (2006) Tendon and neurovascular bundle displacement in the palm with hand flexion and extension: an MRI and gross anatomy correlative study. J Magn Reson Imaging 23:742-6

Showing the most recent 10 out of 36 publications