Less than 1% of the total body magnesium is present in the peripheral blood. We developed an assay to determine the magnesium content and concentration of blood mononuclear cells as an index for intracellular magnesium and/or total body magnesium status. We determined plasma, red blood cell and mononuclear blood cell magnesium concentrations in normal individuals between the ages of twenty and seventy. We determined these same magnesium parameters in women with the premenstrual syndrome and the control group at four points during the menstrual cycle. The results show magnesium parameters do not differ with age. The magnesium concentration of red blood cells decreases significantly during the menstrual cycle in women with the premenstrual syndrome.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL010010-14
Application #
3916509
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
14
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Lane, Jason W; Rehak, Nadja N; Hortin, Glen L et al. (2008) Pseudohyperphosphatemia associated with high-dose liposomal amphotericin B therapy. Clin Chim Acta 387:145-9
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