The purpose of this project was to extend existing human movement analysis methodology by developing an analytical technique (induced acceleration analysis) that can provide direct estimates of the influence of muscular effort on the movement of all joints and body segments, and overall functional movement task performance. Applying the technique to data from a group of normal walkers clearly indicated that the muscles that cross the ankle joint are the primary contributors to normal walking performance. Clinical case studies involving patients with physical impairments have revealed a vast array of compensatory movement control strategies. The ability to accurately predict the effects of disease and treatment on an individuals ability to function relies entirely on our capacity to understand the complex process that transforms muscular effort into functional movements. The induced acceleration analysis technique is the first of its kind capable of relating muscular effort to the control of com-plex functional movement tasks. This capability adds significantly to the foundation on which our ability to ultimately understand the influence of disease on function and pre-dict the onset of disability will rest.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL060017-09
Application #
6289491
Study Section
Special Emphasis Panel (RM)
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Goldberg, Saryn R; Stanhope, Steven J (2013) Sensitivity of joint moments to changes in walking speed and body-weight-support are interdependent and vary across joints. J Biomech 46:1176-83
Goldberg, Saryn R; Kepple, Thomas M (2009) Muscle-induced accelerations at maximum activation to assess individual muscle capacity during movement. J Biomech 42:952-5
Mazza, Claudia; Stanhope, Steven J; Taviani, Antonio et al. (2006) Biomechanic modeling of sit-to-stand to upright posture for mobility assessment of persons with chronic stroke. Arch Phys Med Rehabil 87:635-41
Siegel, Karen Lohmann; Kepple, Thomas M; Stanhope, Steven J (2006) Using induced accelerations to understand knee stability during gait of individuals with muscle weakness. Gait Posture 23:435-40
Manal, Kurt; Chang, Chih-Chung; Hamill, Joseph et al. (2005) A three-dimensional data visualization technique for reporting movement pattern deviations. J Biomech 38:2151-6
Slobounov, S; Hallett, M; Stanhope, S et al. (2005) Role of cerebral cortex in human postural control: an EEG study. Clin Neurophysiol 116:315-23
Siegel, Karen Lohmann; Kepple, Thomas M; Stanhope, Steven J (2004) Joint moment control of mechanical energy flow during normal gait. Gait Posture 19:69-75
Mazza, Claudia; Benvenuti, Francesco; Bimbi, Carlo et al. (2004) Association between subject functional status, seat height, and movement strategy in sit-to-stand performance. J Am Geriatr Soc 52:1750-4
Manal, Kurt; Stanhope, Steven J (2004) A novel method for displaying gait and clinical movement analysis data. Gait Posture 20:222-6
Manal, K; McClay Davis, I; Galinat, B et al. (2003) The accuracy of estimating proximal tibial translation during natural cadence walking: bone vs. skin mounted targets. Clin Biomech (Bristol, Avon) 18:126-31

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