Abstract

This project involves collaborative work with NIH scientists, in which sophisticated mathematical tools or an acquaintance with theoretical methods in the physical sciences are required for the research. The problems dealt with here are generalizations of those suggested by investigations dealt with under the heading of Instrumental Analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Center for Information Technology (CIT)
Type
Intramural Research (Z01)
Project #
1Z01CT000024-26
Application #
6680228
Study Section
(MSCL)
Project Start
Project End
Budget Start
Budget End
Support Year
26
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Computer Research and Technology
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Shvartsman, Stanislav Y; Coppey, Mathieu; Berezhkovskii, Alexander M (2008) Dynamics of maternal morphogen gradients in Drosophila. Curr Opin Genet Dev 18:342-7
Vazquez, Marco-Vinicio; Berezhkovskii, Alexander M; Dagdug, Leonardo (2008) Diffusion in linear porous media with periodic entropy barriers: A tube formed by contacting spheres. J Chem Phys 129:046101
Berezhkovskii, Alexander M; Bezrukov, Sergey M (2008) Fluctuation theorem for channel-facilitated membrane transport of interacting and noninteracting solutes. J Phys Chem B 112:6228-32
Berezhkovskii, Alexander M; Weiss, George H (2008) Propagators and related descriptors for non-Markovian asymmetric random walks with and without boundaries. J Chem Phys 128:044914
Berezhkovskii, Alexander M; Bezrukov, Sergey M (2008) Counting translocations of strongly repelling particles through single channels: fluctuation theorem for membrane transport. Phys Rev Lett 100:038104
Coppey, Mathieu; Boettiger, Alistair N; Berezhkovskii, Alexander M et al. (2008) Nuclear trapping shapes the terminal gradient in the Drosophila embryo. Curr Biol 18:915-9
Coppey, Mathieu; Berezhkovskii, Alexander M; Kim, Yoosik et al. (2007) Modeling the bicoid gradient: diffusion and reversible nuclear trapping of a stable protein. Dev Biol 312:623-30
Bezrukov, Sergey M; Berezhkovskii, Alexander M; Szabo, Attila (2007) Diffusion model of solute dynamics in a membrane channel: mapping onto the two-site model and optimizing the flux. J Chem Phys 127:115101
Dagdug, Leonardo; Berezhkovskii, Alexander M; Makhnovskii, Yurii A et al. (2007) Transient diffusion in a tube with dead ends. J Chem Phys 127:224712
Berezhkovskii, A M; Pustovoit, M A; Bezrukov, S M (2007) Diffusion in a tube of varying cross section: numerical study of reduction to effective one-dimensional description. J Chem Phys 126:134706

Showing the most recent 10 out of 32 publications