Delta-9-tetrahydrocannabinol (THC) has been hypothesized to influence immune function. However, this has not been investigated in a comprehensive fashion in humans. The purpose of this study is to measure and study the effects of THC on immune function. To investigate immune-endocrine correlations, hormone parameters defining the activity of the hypothalamo-pituitary-adrenal axis have been measured during THC administration. (The effects of THC on cognitive function will also be investigated.) Experienced THC users have been recruited for study. Immune function of lymphocytes in vitro has been investigated during orally administered and inhaled THC and during the washout phase.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Intramural Research (Z01)
Project #
1Z01DA000020-04
Application #
3853668
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
National Institute on Drug Abuse
Department
Type
DUNS #
City
State
Country
United States
Zip Code