1. Triple-helix DNAWe have now determined the three-dimensional structure of an oligodeoxynucleotide which exibits a triplex form of association. This structure has been determined at 1.7A resolution. This is the first determination of a significant stretch of triplex DNA and reveals the changes in dimensions that occur as duplex proceeds to triplex.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Intramural Research (Z01)
Project #
1Z01DK034003-31
Application #
6289772
Study Section
Special Emphasis Panel (LMB)
Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1999
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code