Phenylalanine hydroxylase activity, measured at neutral pH, can be markedly increased by a brief exposure of the enzyme to alkaline pH. Phenylalanine given to rats leads to an enhanced phosphorylation and activation of hepatic phenylalanine hydroxylase.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Intramural Research (Z01)
Project #
1Z01MH001031-20
Application #
3944671
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
20
Fiscal Year
1987
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
DUNS #
City
State
Country
United States
Zip Code