Physiological Analysis of Voluntary Movement

Hallett, M.

Abstract

A laboratory is being set up for analysis of balance. This will enable simultaneous study of body angles, foot-floor forces and multiple EMGs. We hope to identify normal mechanisms of balance and how these are deranged in patients. The study of motor control in hemiplegia is being set up as the major project of the Unit. Patients with discrete brain lesions will be studied; patients with strokes will be the main group, and many patients will be followed serially from onset of the disorder to recovery. We hope to discover pathophysiological mechanisms including those mechanisms underlying recovery. Methods of study will include (1) quantitative clinical battery, (2) evoked potentials, (3) pre-motor potentials, (4) stretch reflexes, (5) EMG analysis of voluntary movements, and (6) PET scanning during voluntary movement.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Intramural Research (Z01)
• Project #: 1Z01NS002669-01
• Application #: 4696969
• Support Year: 1
• Fiscal Year: 1985

Institution

• Name: National Institute of Neurological Disorders and Stroke
• Country: United States

Publications

Karabanov, Anke Ninija; Chao, Chi-Chao; Paine, Rainer et al. (2013) Mapping different intra-hemispheric parietal-motor networks using twin Coil TMS. Brain Stimul 6:384-9

Wheaton, Lewis; Fridman, Esteban; Bohlhalter, Stephan et al. (2009) Left parietal activation related to planning, executing and suppressing praxis hand movements. Clin Neurophysiol 120:980-6

Shin, Hae-Won; Sohn, Young H; Hallett, Mark (2009) Hemispheric asymmetry of surround inhibition in the human motor system. Clin Neurophysiol 120:816-9

Hattori, Noriaki; Shibasaki, Hiroshi; Wheaton, Lewis et al. (2009) Discrete parieto-frontal functional connectivity related to grasping. J Neurophysiol 101:1267-82

Nahab, Fatta B; Hattori, Noriaki; Saad, Ziad S et al. (2009) Contagious yawning and the frontal lobe: an fMRI study. Hum Brain Mapp 30:1744-51

Kayagil, Turan A; Bai, Ou; Henriquez, Craig S et al. (2009) A binary method for simple and accurate two-dimensional cursor control from EEG with minimal subject training. J Neuroeng Rehabil 6:14

Bohlhalter, S; Hattori, N; Wheaton, L et al. (2009) Gesture subtype-dependent left lateralization of praxis planning: an event-related fMRI study. Cereb Cortex 19:1256-62

Hortobagyi, Tibor; Richardson, Sarah Pirio; Lomarev, Mikhael et al. (2009) Chronic low-frequency rTMS of primary motor cortex diminishes exercise training-induced gains in maximal voluntary force in humans. J Appl Physiol 106:403-11

Wheaton, Lewis A; Bohlhalter, Stephan; Nolte, Guido et al. (2008) Cortico-cortical networks in patients with ideomotor apraxia as revealed by EEG coherence analysis. Neurosci Lett 433:87-92

Bai, Ou; Lin, Peter; Vorbach, Sherry et al. (2008) A high performance sensorimotor beta rhythm-based brain-computer interface associated with human natural motor behavior. J Neural Eng 5:24-35