Current studies in the Cognitive Neuroscience Section focus on amnesia, thinking, neurolinguistics, event-related evoked potentials, social cognition, and visual processing. Goth single-case and group design studies are used. Normal controls, inpatients and outpatients are evaluated. Memory is studied in experiments focusing on implicit and explicit retrieval, priming, autobiographical recall, discourse processing, naming and word retrieval, and categorization tasks, Reasoning and problem-solving are studied in experiments focusing on planning, syllogisms, analogical thinking, and schema organization. Dyslexia, dysgraphia, and dysnomia, are studied in experiments focusing on single word reading and writing, lexical decision, associative and semantic priming, and similar tasks. Event-related evoked potentials are measured for latency, amplitude, and distribution and used as a physiologic index of information-processing stages, working memory, visual attention, and automatic processing. Emotions, impression and preference formation, and social judgment are studied in experiments focusing on judgment of interpersonal behavior, word association, and mood state. Finally, visual information processing is studied, beginning with experiments examining spatial frequency contrast-sensitivity, object recognition, and visual categorization. Although developing theoretically valid and testable models of cognitive processing is the primary aim of the Section, there is also a strong effort to relate the profile of cognitive processing to brain regions and systems. Pharmacologic challenge and infusion studies are planned to evaluate the dissociability of hypothesized components of memory processing, MRI functional stimulation and PET scan studies are planned to examine whether plans are processed in a unique brain location.
| Goel, Vinod; Lam, Elaine; Smith, Kathleen W et al. (2017) Lesions to polar/orbital prefrontal cortex selectively impair reasoning about emotional material. Neuropsychologia 99:236-245 |
| Zhong, Wanting; Cristofori, Irene; Bulbulia, Joseph et al. (2017) Biological and cognitive underpinnings of religious fundamentalism. Neuropsychologia 100:18-25 |
| Barbey, Aron K; Colom, Roberto; Grafman, Jordan (2013) Architecture of cognitive flexibility revealed by lesion mapping. Neuroimage 82:547-54 |
| Koenigs, Michael; Huey, Edward D; Raymont, Vanessa et al. (2008) Focal brain damage protects against post-traumatic stress disorder in combat veterans. Nat Neurosci 11:232-7 |
| Schooler, Carmi; Caplan, Leslie J; Revell, Andrew J et al. (2008) Brain lesion and memory functioning: short-term memory deficit is independent of lesion location. Psychon Bull Rev 15:521-7 |
| Zamboni, G; Huey, E D; Krueger, F et al. (2008) Apathy and disinhibition in frontotemporal dementia: Insights into their neural correlates. Neurology 71:736-42 |
| Krueger, Frank; McCabe, Kevin; Moll, Jorge et al. (2007) Neural correlates of trust. Proc Natl Acad Sci U S A 104:20084-9 |
| Solomon, Jeffrey; Raymont, Vanessa; Braun, Allen et al. (2007) User-friendly software for the analysis of brain lesions (ABLe). Comput Methods Programs Biomed 86:245-54 |
| Zahn, Roland; Moll, Jorge; Krueger, Frank et al. (2007) Social concepts are represented in the superior anterior temporal cortex. Proc Natl Acad Sci U S A 104:6430-5 |
| Frattali, Carol; Hanna, Rebecca; McGinty, Anita Shukla et al. (2007) Effect of prefrontal cortex damage on resolving lexical ambiguity in text. Brain Lang 102:99-113 |
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