Measurement of the hemoglobin oxygen equilibrium curve (OEC) in an automated system is hampered by noise. To obtain reliable results in reading partial pressures with an accuracy of 0.01 mmHg requires special techniques in electronic circuit design. The p02, pH, and the pCO2 electrodes have very high internal resistance with very low output signal levels. When these devices are used in an environment contaminated by radio frequency interference (RFI) from a computer, the magnetic fields of stepping motors, as well as power line transients generated by 'a high current water bath, the electrode output leads must be kept short and shielded. The electrode signals must be kept scaled and offset by a computer-controlled signal processor that properly interfaces these voltages to an AT-type personal computer, for further software analysis. Another task to be performed is the designing and fabrication of the required circuitry for the development of the automated system to perform the desired measurements.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Intramural Research (Z01)
Project #
1Z01RR010267-04
Application #
3896181
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
National Center for Research Resources
Department
Type
DUNS #
City
State
Country
United States
Zip Code