This program is involved in many aspects of information technology support for the NCI Center for Cancer Research (CCR). Projects which we develop and/or maintain include the following: 1) Labmatrix, a tissue research and inventory system for managing both the collection and storage of tissues, as well as data resulting from the research analysis of these tissues. 2) iRIS, a protocol lifecycle management system used for all CCR human and animal protocols as well as DCEG Special Studies IRB-managed protocols. 3) CCR Protocol View, a website for NCI and NIH Clinical Center distribution of our clinical trials protocols. 4) Confluence wiki, which facilitates standardized documentation, collaboration, and simple website development for CCR scientific and administrative staff. Confluence acts as an interface to our DB Quick technology, allowing ultra fast development of simple web-based database applications. 5) JIRA issue management software, used to support those groups in the CCR that need to manage user requests. 6) Future Fellows, a web application for the collection and review of C.V.s submitted by potential postdoctoral fellows. 7) Budget Management System, used to allocate funds to CCR principal investigators and core research groups. 8) Redesign and reengineering of the CCR website to a Drupal-based site. 9) CCR Referrals. This provides a standardized way to manage potential clinical trial participants and their medical information as it pertains to being qualified to participate in CCR clinical trials. 10) PA Tracker for the tracking of human resource packages through the approval process. 11) Video conference support for scientific presentations, including the CCR Grand Rounds and Eminent Lecture series, as well as many smaller scientific collaborations. 11) Section 508 compliance of CCR-managed websites. 12) Scribe, a method of collecting study data directly from study subjects and having that data go through real-time validation and entry into a researcher's data collection system.