The scaling of CMOS technologies has delivered astronomical increases in transistor density and performance, leading to more chip functionality at higher speeds. Several problems are expected to plague nanometer designs: robustness to process and operating variations; long-term reliability due to electromigration and soft errors; and power density, with static power density approaching or exceeding the dynamic one. Novel solutions spanning materials, devices, circuits, microarchitectures and Computer-Aided Design (CAD) tools are required to overcome these problems. We focus in this proposal on CAD tools for double-gate devices, novel transistor structures with more than one gate terminal to control the transistor channel. Compared to MOSFETs, double-gate devices promise substantial improved control over leakage current and short channel effects while delivering high drive currents.