This award from the Inorganic, Bioinorganic and Organometallic Chemistry Program and the Biochemistry Program provides the third year of a three-year continuing grant to support the work of Dr. Jacqueline K. Barton of the California Institute of Technology. In collaboration with Dr. Lawrence A. Chasin of Columbia University, Dr. Barton will evaluate the usefulness of chiral metal complexes as probes of the secondary structure of DNA. Such metal complexes have proven useful in identifying segments of DNA with altered conformations, such as the so-called Z-DNA and cruciform DNA.

Agency
National Science Foundation (NSF)
Institute
Division of Chemistry (CHE)
Type
Standard Grant (Standard)
Application #
9011622
Program Officer
Jon F. Parcher
Project Start
Project End
Budget Start
1990-05-15
Budget End
1992-04-30
Support Year
Fiscal Year
1990
Total Cost
$75,950
Indirect Cost
Name
California Institute of Technology
Department
Type
DUNS #
City
Pasadena
State
CA
Country
United States
Zip Code
91125