The generative entrenchment of an entity is a measure of how much of the generated structure or activity of a complex system depends upon the presence or activity of that entity. It has been demonstrated that entities with higher degrees of generative entrenchment tend to be more conservative in evolutionary changes of such systems. Models of complex structures incorporating the effects of generative entrenchment have demonstrated their relevance in analyzing and explaining a variety of developmental and evolutionary phenomena. Professor Wimsatt and his graduate student will extend prior simulations and analyses of a variety of cases, problems and investigations of a number or results on the evolution of gene control networks. They will extend the work of Kauffman, of their own work, and others to investigate the influence of different degrees of generative entrenchment on the behavior of these networks and their evolution. Since virtually any system exhibits differential degrees of generative entrenchment among its parts and activities, these studies and results have in addition broad potential application for theoretical, simulation, and experimental analyses in a number of areas. These areas include: developmental programs and their significance for evolution, macroevolutionary change, the innate- acquired distinction and investigations using it in linguistics and cognitive psychology, developmental constraints, constraints on the evolution of complex adaptations, and even in the analyses of scientific change.

Agency
National Science Foundation (NSF)
Institute
Division of Biological Infrastructure (DBI)
Type
Standard Grant (Standard)
Application #
8807869
Program Officer
Ronald J. Overmann
Project Start
Project End
Budget Start
1988-07-01
Budget End
1990-06-30
Support Year
Fiscal Year
1988
Total Cost
$25,000
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60637