We have recently demonstrated that a new form of near field scanning optical microscopy based on a small (e.g. 35 nm diameter)Ag sphere, excited at its plasmon resonant frequency, can achieve sub-wavelength magnetic Kerr imaging. We propose to develop a suitably modified microscope based on these Ag plasmon resonators, but specifically optimized for high resolution fluorescence imaging. We believe that the detection of individual fluorophores with near molecular resolution may be possible. Example are given of exciting new opportunities in bio-medical research that will become practicable when our new microscope is operative.

Agency
National Science Foundation (NSF)
Institute
Division of Biological Infrastructure (DBI)
Type
Standard Grant (Standard)
Application #
9415294
Program Officer
Michael K. Lamvik
Project Start
Project End
Budget Start
1995-01-15
Budget End
1996-12-31
Support Year
Fiscal Year
1994
Total Cost
$46,728
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92093