Funds are requested for acquisition of a time-of-flight, matrix-assisted laser desorption ionization mass spectrometer (TOF-MALDI-MS) for analysis of proteins, covalent protein-ligand complexes, glycopeptides, phosphopeptides, designed peptides with nonprotein amino acids, photoaffinity modified peptides, and enzymatic digests of posttranslationally-modified proteins. Projects will be conducted by seven major faculty users from the departments of Chemistry, Biochemistry & Cell Biology, Allergy, Rheumatology & Clinical Immunology, and Physiology & Biophysics whose research requires analysis of modified peptides. The instrument will be housed in the Center for the Analysis and Synthesis of Macromolecules in the Department of Physiology & Biophysics and operated as a user-accessible, operator-maintained shared facility. The Center for Biotechnology, a New York State Center for Advanced Technology will provide staffing and administrative oversight for the instrument.

Agency
National Science Foundation (NSF)
Institute
Division of Biological Infrastructure (DBI)
Type
Standard Grant (Standard)
Application #
9419980
Program Officer
Lee C. Makowski
Project Start
Project End
Budget Start
1995-02-15
Budget End
1997-01-31
Support Year
Fiscal Year
1994
Total Cost
$70,000
Indirect Cost
Name
State University New York Stony Brook
Department
Type
DUNS #
City
Stony Brook
State
NY
Country
United States
Zip Code
11794