We have established the feasibility of observing non-equilibrium fluctuations in liquids subjected to a temperature gradient by small-angle Rayleigh scattering. We propose to apply this technique to study non-equilibrium fluctuations in liquid mixtures, macromolecular systems and colloidal suspensions. Concomitant with the light-scattering work, Soret phenomena will be investigated with an optional beam-bending technique.