Project Summary, 2005 Epigenetics Gordon Research Conference
The study of epigenetics concerns the enormously complex mechanisms by which genotype gives rise to phenotype. It pertains to every aspect of development in virtually all organisms and has been a good reminder that the essence of how genotype gives rise to phenotype does not, after all, reside completely in DNA. This proposal requests support for the sixth Gordon Research Conference on Epigenetics to be held at Holderness School, New Hampshire, August 7-12, 2005. Invited speakers are leading researchers working on prokaryotes, fungi, ciliates, plants, worms, insects, and mammals, and their presentations will cover some of the most fascinating areas of science today, including molecular and cellular memory, cellular de-differentiation, DNA asymmetry, DNA methylation, RNA interference, parental imprinting, X-chromosome inactivation, paramutation, ploidy, switching, environmental stress, genome defense systems, position effects, histone modifications, mammalian cloning, and stem cell development. Of particular interest are newly-recognized phenomena whose underlying mechanisms are currently mysterious.
The 2005 Gordon Research Conference on Epigenetics will provide a unique setting for researchers working on this broad spectrum of mechanisms and organisms to come together and exchange results and ideas. With a limited enrollment and ample time for formal and informal discussions, the cross-disciplinary environment of this conference will foster the innovative thinking and novel collaborations that are critical for the success of researchers in the field of epigenetics. Finally, as has always been the case with this series, the 2005 Conference will place a high priority on promoting the science and careers of young investigators and increasing the diversity of the scientific community.
