Great progress is being made on understanding exactly how sex steroids act on the nervous system to yield adaptive behavior and physiology that serves to promote reproductive success. Dr. Adkins-Regan is performing experiments on birds which investigates the spinal level neuroendocrine processes. This work will contribute to our understanding of the role of testosterone metabolites in androgenic actions on the nervous system. Dr. Adkins-Regan has data that show that these sex steroids change the dendritic arborizations of motor neurons. This finding has ramifications for neuronal plasticity in the adult. This work is important because there is increasing recognition that in addition to specific reproduction related effects on the nervous system such as the production of sexual dimorphism, sex hormones may have more general trophic effects on neural development. Neuroendocrinology is a tremendously fast moving field, and its study should yield many new findings regarding the physiology of human behavior.

Agency
National Science Foundation (NSF)
Institute
Division of Integrative Organismal Systems (IOS)
Type
Standard Grant (Standard)
Application #
8809441
Program Officer
Christopher Comer
Project Start
Project End
Budget Start
1988-08-15
Budget End
1992-07-31
Support Year
Fiscal Year
1988
Total Cost
$149,980
Indirect Cost
Name
Cornell University
Department
Type
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850