The function of the brain, memory and learning and behavior is critically dependent on nerve cells to transmit, process and store information. To fulfill these tasks neurons possess unique structures - extensions of their cell body (dendrites and axons)- that terminate (synapse) on other cells to allow electrical and chemical communication between them. These synaptic junctions are the localized sites where neurotransmitters are stored, released, synthesized and recycled. The characterization of the molecular and chemical components of the synapse such as the protein SNAP-25, is an important goal of research in the understanding of the nervous system. SNAP-25 is a prominent protein found in nerve terminals of the mature nervous system only and seems to be preserved up through the animal kingdom suggesting that it has important nervous system function.

Agency
National Science Foundation (NSF)
Institute
Division of Integrative Organismal Systems (IOS)
Application #
9121121
Program Officer
Project Start
Project End
Budget Start
1992-04-01
Budget End
1995-09-30
Support Year
Fiscal Year
1991
Total Cost
$277,555
Indirect Cost
Name
The Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037