9407826 McLoon ABSTRACT The extraocular muscles, the muscles that move the eye in the orbit, are different from other mature skeletal muscles in mammals. They have a number of characteristics seen only in immature or regenerating muscle, such as the continued expression of immature or embryonic proteins and as well as immature patterns of innervation. This study proposes to examine the possibility that either these muscles fail to fully mature or that the extraocular muscles, unlike other skeletal muscles continue to divide in the mature mammal to produce new muscle fibers. This will hopefully shed light on possible mechanisms that control when and how muscle cells divide.

Agency
National Science Foundation (NSF)
Institute
Division of Integrative Organismal Systems (IOS)
Type
Standard Grant (Standard)
Application #
9407826
Program Officer
Christopher Platt
Project Start
Project End
Budget Start
1994-08-15
Budget End
1996-07-31
Support Year
Fiscal Year
1994
Total Cost
$48,848
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
City
Minneapolis
State
MN
Country
United States
Zip Code
55455