9727762 Bennett This study examines how the pulmonary and cardiovascular systems respond to increased metabolic demands for increased oxygen delivery and carbon dioxide removal in very different tissues: the skeletal musculature and the intestine. Is the pattern of increased ventilation and circulation stereotyped, such that the same response (heart rate, stroke volume, breathing frequency, and tidal volume) is used for equal energetic demands in the two different tissues, or is it plastic, dependent on which tissue is active? If both tissues are active simultaneously, which receives priority allocation for oxygen delivery and carbon dioxide removal? Large reptiles will be used as model systems to investigate these patterns, because metabolic increments associated with digestion are extraordinarily large in these animals, approaching those associated with physical activity.

Agency
National Science Foundation (NSF)
Institute
Division of Integrative Organismal Systems (IOS)
Application #
9727762
Program Officer
William E. Zamer
Project Start
Project End
Budget Start
1998-01-01
Budget End
2001-12-31
Support Year
Fiscal Year
1997
Total Cost
$243,000
Indirect Cost
Name
University of California Irvine
Department
Type
DUNS #
City
Irvine
State
CA
Country
United States
Zip Code
92697