Patellofemoral pain (PFP) syndrome is one of the most common abnormalities involving the knee. Current literature suggests a multifactorial etiology and it is commonly accepted that abnormal patellar tracking, patellar malalignment, and quadriceps imbalance are closely related to PFP. The purpose of the proposed research is to determine whether imbalances in the soft tissue structures surrounding the knee contribute to PFP by inducing pain secondary to patellar malalignment and maltracking. A noninvasive system for in vivo measurement of patellar movement in six degrees-of-freedom will be designed and validated. Development of quantitative diagnostic tools for PFP could lead to better characterization of PFP syndrome, allowing treatment methods to be tailored to individual needs and leading to improved functional outcomes. The diagnostic system will then be used to quantify patellar maltracking in PFP subjects. Finally, we will attempt to elucidate the nature of the quadriceps imbalance which leads to patellar maltracking in PFP. A thorough understanding of the etiology of PFP will highlight future research directions for this syndrome. We propose to develop a more cohesive picture of the underlying neuromechanical mechanisms of PFP syndrome; such that we may evaluate the pathological changes associated with PFP accurately, and improve functional outcomes due to more effective treatment methods for PFP syndrome.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31EB005169-02
Application #
7125439
Study Section
Special Emphasis Panel (ZRG1-F10 (20))
Program Officer
Erim, Zeynep
Project Start
2005-09-19
Project End
2007-09-18
Budget Start
2006-09-19
Budget End
2007-09-18
Support Year
2
Fiscal Year
2006
Total Cost
$35,332
Indirect Cost
Name
Rehabilitation Institute of Chicago
Department
Type
DUNS #
068477546
City
Chicago
State
IL
Country
United States
Zip Code
60611
Wilson, Nicole A; Mazahery, B Tom; Koh, Jason L et al. (2010) Effect of bracing on dynamic patellofemoral contact mechanics. J Rehabil Res Dev 47:531-41