Molecular Mechanisms of Desensitization in the Iris

Honkanen, Richard E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Eye Institute (NEI)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 1F32EY006050-01
• Application #: 3039018
• Study Section: Vision Research and Training Committee (VSN)
• Project Start: 1987-11-28
• Budget Start: 1987-07-01
• Budget End: 1988-06-30
• Support Year: 1
• Fiscal Year: 1987

Institution

• Name: Medical College of Georgia (MCG)
• Type: Schools of Medicine
• City: Augusta
• State: GA
• Country: United States
• Zip Code: 30912

Publications

Honkanen, R E; Dukelow, M; Zwiller, J et al. (1991) Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases. Mol Pharmacol 40:577-83

Honkanen, R E; Howard, E F; Abdel-Latif, A A (1990) M3-muscarinic receptor subtype predominates in the bovine iris sphincter smooth muscle and ciliary processes. Invest Ophthalmol Vis Sci 31:590-3

Honkanen, R E; Abdel-Latif, A A (1989) Muscarinic-agonist and guanine nucleotide stimulation of myo-inositol trisphosphate formation in membranes isolated from bovine iris sphincter smooth muscle: effects of short-term cholinergic desensitization. Membr Biochem 8:39-59

Honkanen, R E; Abdel-Latif, A A (1988) Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochem Pharmacol 37:2575-83

Honkanen, R E; Abdel-Latif, A A (1988) AFDX-116 discriminates between muscarinic M2 receptors of the heart and the iris smooth muscle. Mol Cell Biochem 82:131-5